[HTML][HTML] Regulation of post-translational modification of PD-L1 and advances in tumor immunotherapy
C Feng, L Zhang, X Chang, D Qin, T Zhang - Frontiers in Immunology, 2023 - frontiersin.org
The immune checkpoint molecules programmed cell death receptor 1 (PD-1) and
programmed death ligand 1 (PD-L1) are one of the most promising targets for tumor …
programmed death ligand 1 (PD-L1) are one of the most promising targets for tumor …
[HTML][HTML] Recent advances in drug discovery for triple-negative breast cancer treatment
Triple-negative breast cancer (TNBC) is one of the most heterogeneous and aggressive
breast cancer subtypes with a high risk of death on recurrence. To date, TNBC is very …
breast cancer subtypes with a high risk of death on recurrence. To date, TNBC is very …
[HTML][HTML] NEK2 inactivates the Hippo pathway to advance the proliferation of cervical cancer cells by cooperating with STRIPAK complexes
YR Zhang, PS Zheng - Cancer Letters, 2022 - Elsevier
The never in mitosis gene A (NIMA)-related kinase 2 (NEK2) protein has been reported to be
an oncoprotein that plays different oncogenic roles in multiple cancers. Here, we confirmed …
an oncoprotein that plays different oncogenic roles in multiple cancers. Here, we confirmed …
[HTML][HTML] NEK2 promotes the migration and proliferation of ESCC via stabilization of YAP1 by phosphorylation at Thr-143
W Su, H Hu, Q Ding, M Wang, Y Zhu, Z Zhang… - Cell Communication and …, 2022 - Springer
Abstract Background Esophageal Squamous Cell Carcinoma (ESCC) was characterized as
a regional-prevalent and aggressive tumor with high morbidity and mortality. NIMA-related …
a regional-prevalent and aggressive tumor with high morbidity and mortality. NIMA-related …
[HTML][HTML] The clinicopathological characteristics, prognosis and immune microenvironment mapping in MSI-H/MMR-D endometrial carcinomas
Y Guo, Y Liu, W Zhang, H Luo, P Shu, G Chen, Y Li - Discover Oncology, 2022 - Springer
Endometrial cancer had a relatively high prevalence of MMR deficiency. MMR-D/MSI-H
endometrial cancer patients are suggested to be potential beneficiaries of PD-1/PD-L1 …
endometrial cancer patients are suggested to be potential beneficiaries of PD-1/PD-L1 …
[HTML][HTML] NEK2 promotes esophageal squamous cell carcinoma cell proliferation, migration and invasion through the Wnt/β-catenin signaling pathway
D Guo, W Yao, X Du, J Dong, X Zhang, W Shen… - Discover Oncology, 2023 - Springer
Objectives The NEK2 (never in mitosis gene A-related kinase 2), a serine/threonine kinase
involved in chromosome instability and tumorigenesis. Hence, this study aimed to explore …
involved in chromosome instability and tumorigenesis. Hence, this study aimed to explore …
Primary cilia: Structure, dynamics, and roles in cancer cells and tumor microenvironment
YT Guan, C Zhang, HY Zhang, WL Wei… - Journal of Cellular …, 2023 - Wiley Online Library
Despite the initiation of tumor arises from tumorigenic transformation signaling in cancer
cells, cancer cell survival, invasion, and metastasis also require a dynamic and reciprocal …
cells, cancer cell survival, invasion, and metastasis also require a dynamic and reciprocal …
[HTML][HTML] Differential Expression of NEK Kinase Family Members in Esophageal Adenocarcinoma and Barrett's Esophagus
Simple Summary In the present study, we analyzed gene expression of NEK family
members (NEK1-NEK11) in esophageal adenocarcinoma (EAC) and its precancerous …
members (NEK1-NEK11) in esophageal adenocarcinoma (EAC) and its precancerous …
CCNA2 and NEK2 regulate glioblastoma progression by targeting the cell cycle
HY Zhou, YC Wang, T Wang, W Wu… - Oncology …, 2024 - spandidos-publications.com
Glioblastoma (GBM) is characterized by significant heterogeneity, leading to poor survival
outcomes for patients, despite the implementation of comprehensive treatment strategies …
outcomes for patients, despite the implementation of comprehensive treatment strategies …
[HTML][HTML] Identification of tumor antigens and immune subtypes of hepatocellular carcinoma for mRNA vaccine development
TL Lu, CL Li, YQ Gong, FT Hou… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Identification of tumor antigens and immune subtypes of hepatocellular carcinoma for mRNA
vaccine development - PMC Back to Top Skip to main content NIH NLM Logo Access keys …
vaccine development - PMC Back to Top Skip to main content NIH NLM Logo Access keys …