Neutrophils have recently emerged as promising carriers for drug delivery due to their
unique properties including rapid response toward inflammation, chemotaxis, and …

Rheumatoid arthritis (RA) is the most prevalent inflammatory joint disease worldwide,
leading to irreversible disability and even mortality. Unfortunately, current treatment …

Acute myocardial infarction (MI) remains a serious disease causing lots of death and
disability worldwide. Early and effective application of thrombolytic therapy or primary …

Atherosclerosis, a chronic inflammatory disease, is the primary cause of myocardial
infarction and ischemic stroke. Recent studies have demonstrated that dysregulation of yes …

Myocardial ischaemia is pathologically complicated; various changes in intracellular and
extracellular microenvironments make it essential to develop a smart drug system with …

Severe acute pancreatitis (AP) is a life-threatening pancreatic inflammatory disease with a
high mortality rate (∼ 40%). Existing pharmaceutical therapies in development or in clinical …

Vascular diseases constitute a significant contributor to worldwide mortality rates, placing a
substantial strain on healthcare systems and socio-economic aspects. They are closely …

Aim: This study aimed to develop biomimetic nanoparticles (NPs) of roflumilast (ROF) for
attenuating myocardial ischemia/reperfusion (MI/R) injury. Materials & methods: We …

Myocardial infarction (MI) is a global cardiovascular disease with high mortality and
morbidity. To treat acute MI, various therapeutic approaches have been developed …

Little evidence demonstrated the effects of nitric oxide (NO) hydrogel with adipocytes in vivo.
We aimed to investigate the effects of adiponectin (ADPN) and CCR2 antagonist on cardiac …