[HTML][HTML] Obesity, diabetes, and increased cancer progression

DS Kim, PE Scherer - Diabetes & metabolism journal, 2021 - synapse.koreamed.org
Rates of obesity and diabetes have increased significantly over the past decades and the
prevalence is expected to continue to rise further in the coming years. Many observations …

[HTML][HTML] Pathophysiology of obesity and its associated diseases

X Jin, T Qiu, L Li, R Yu, X Chen, C Li, CG Proud… - … Pharmaceutica Sinica B, 2023 - Elsevier
The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

Molecular mechanisms of western diet-induced obesity and obesity-related carcinogenesis—A narrative review

D Lathigara, D Kaushal, RB Wilson - Metabolites, 2023 - mdpi.com
The present study aims to provide a narrative review of the molecular mechanisms of
Western diet-induced obesity and obesity-related carcinogenesis. A literature search of the …

Adiponectin triggers breast cancer cell death via fatty acid metabolic reprogramming

DV Pham, PH Park - Journal of Experimental & Clinical Cancer Research, 2022 - Springer
Background Adiponectin, the most abundant adipokine derived from adipose tissue, exhibits
a potent suppressive effect on the growth of breast cancer cells; however, the underlying …

The role of selected adipocytokines in ovarian cancer and endometrial cancer

S Stępień, P Olczyk, J Gola, K Komosińska-Vassev… - Cells, 2023 - mdpi.com
Due to their multidirectional influence, adipocytokines are currently the subject of numerous
intensive studies. Significant impact applies to many processes, both physiological and …

Adipokines at the crossroads of obesity and mesenchymal stem cell therapy

DV Pham, TK Nguyen, PH Park - Experimental & Molecular Medicine, 2023 - nature.com
Mesenchymal stem cell (MSC) therapy is an emerging treatment strategy to counteract
metabolic syndromes, including obesity and its comorbid disorders. However, its …

Role of leptin and adiponectin in carcinogenesis

A Bocian-Jastrzębska, A Malczewska-Herman… - Cancers, 2023 - mdpi.com
Simple Summary The involvement of leptin and adiponectin with receptors in the formation
of many types of cancer as well as their impact on the clinical course of cancer patients are …

[HTML][HTML] Retinol-binding protein 4 in obesity and metabolic dysfunctions

PAN Nankam, M Blüher - Molecular and Cellular Endocrinology, 2021 - Elsevier
Excessive increased adipose tissue mass in obesity is associated with numerous co-morbid
disorders including increased risk of type 2 diabetes, fatty liver disease, hypertension …

Dynamic interactions in the tumor niche: how the cross-talk between CAFs and the tumor microenvironment impacts resistance to therapy

O Piwocka, I Piotrowski, WM Suchorska… - Frontiers in Molecular …, 2024 - frontiersin.org
The tumor microenvironment (TME) is a complex ecosystem of cells, signaling molecules,
and extracellular matrix components that profoundly influence cancer progression. Among …

Association of lncRNA MEG3 rs941576 polymorphism, expression profile, and its related targets with the risk of obesity-related colorectal cancer: potential clinical …

MA Senousy, OG Shaker, G Ayeldeen, AF Radwan - Scientific Reports, 2024 - nature.com
The identification of novel screening tools is imperative to empower the early detection of
colorectal cancer (CRC). The influence of the long non-coding RNA maternally expressed …