Risk Factors for Recurrence, Complications and Mortality in Clostridium difficile Infection: A Systematic Review

CN Abou Chakra, J Pepin, S Sirard, L Valiquette - PloS one, 2014 - journals.plos.org
Background Clostridium difficile infection (CDI) can lead to complications, recurrence, and
death. Numerous studies have assessed risk factors for these unfavourable outcomes, but …

Sleeping with the enemy: Clostridium difficile infection in the intensive care unit

F Prechter, K Katzer, M Bauer, A Stallmach - Critical care, 2017 - Springer
Over the last years, there was an increase in the number and severity of Clostridium difficile
infections (CDI) in all medical settings, including the intensive care unit (ICU). The current …

Development and validation of a prediction model for mortality and adverse outcomes among patients with peripheral eosinopenia on admission for Clostridium …

AS Kulaylat, EL Buonomo, KW Scully… - JAMA …, 2018 - jamanetwork.com
Importance Recent evidence from an animal model suggests that peripheral loss of
eosinophils inClostridium difficileinfection (CDI) is associated with severe disease. The …

Effectiveness of Oral Vancomycin for Prevention of Healthcare Facility–Onset Clostridioides difficile Infection in Targeted Patients During Systemic Antibiotic Exposure

SW Johnson, SV Brown, DH Priest - Clinical Infectious Diseases, 2020 - academic.oup.com
Background Limited retrospective data suggest prophylactic oral vancomycin may prevent
Clostridioides difficile infection (CDI). We sought to evaluate the effectiveness of oral …

Epidemiology of Clostridium difficile infection in hospitalized adults and the first isolation of C. difficile PCR ribotype 027 in central China

Y Zhou, L Mao, J Yu, Q Lin, Y Luo, X Zhu, Z Sun - BMC infectious diseases, 2019 - Springer
Background Clostridium difficile infection (CDI) is an emerging healthcare problem in the
world. The purpose of this study was to perform a systematic epidemiological research of …

Multi-institution case–control and cohort study of risk factors for the development and mortality of Clostridium difficile infections in Japan

M Takahashi, N Mori, S Bito - BMJ open, 2014 - bmjopen.bmj.com
Objective To examine risk factors for Clostridium difficile infection (CDI) morbidity and
mortality in Japan. Design Multimethod investigation including a case–control study and …

An epidemiological surveillance study (2021–2022): detection of a high diversity of Clostridioides difficile isolates in one tertiary hospital in Chongqing, Southwest …

Y Cui, C Zhang, Q Jia, X Gong, Y Tan, X Hua… - BMC Infectious …, 2023 - Springer
Background Clostridioides difficile is a bacterium that causes antibiotic-associated infectious
diarrhea and pseudomembranous enterocolitis. The impact of C. difficile infection (CDI) in …

Microbiota-Based Live Biotherapeutic RBX2660 for the Reduction of Recurrent Clostridioides difficile Infection in Older Adults With Underlying Comorbidities

G Tillotson, L Archbald-Pannone… - Open Forum …, 2023 - academic.oup.com
Background Advanced age and underlying comorbidities are associated with greater rates
of recurrence in patients with Clostridioides difficile infection (CDI). Reducing the likelihood …

[HTML][HTML] Characteristics and immunological roles of surface layer proteins in Clostridium difficile

N Mori, T Takahashi - Annals of laboratory medicine, 2018 - synapse.koreamed.org
Clostridium difficile is a major causative agent of antibiotic-associated diarrhea and has
become the most common pathogen of healthcare-associated infection worldwide. The …

Comparison of 3 severity criteria for Clostridium difficile infection

A Gomez-Simmonds, CJ Kubin… - Infection Control & …, 2014 - cambridge.org
Effective severity criteria are needed to guide management of Clostridium difficile infection
(CDI). In this retrospective study, outcomes were compared between patients with mild …