Multiple abnormalities occur in the homeostasis of essential endogenous brain biometals in
age-related neurodegenerative disorders, Alzheimer's disease, Parkinson's disease …

The use of radionuclides in medicine is based largely on the discoveries of two critical
concepts, the “tracer principle” and the “magic bullet”. In 1913, George de Hevesy …

Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …

HAcactsc HAcPytsc HAcPyOtsc HAntsc H, ATS H, BrSatsc HBzPytsc HFoFutsc HFolQtsc
HFoPytsc HFoPyOtsc H, KTS HMIstsc HPictsc 1-acetylacetone thiosemicarbazone 2 …

Neutral and cationic copper bis (thiosemicarbazone) complexes bearing methyl, phenyl, and
hydrogen, on the diketo-backbone of the ligand have been synthesized. All of them were …

The molecules known as bis (thiosemicarbazones) derived from 1, 2-diones can act as
tetradentate ligands for Cu (II), forming stable, neutral complexes. As a family, these …

The chemistry, radiochemistry, radiobiology, and radiopharmacology of
radiopharmaceuticals containing copper radionuclides are reviewed. Copper radionuclides …

The equilibrium of metal ions is critical for many physiological functions, particularly in the
central nervous system, where metals are essential for development and maintenance of …

Cognitive decline in Alzheimer's disease (AD) involves pathological accumulation of
synaptotoxic amyloid-β (Aβ) oligomers and hyperphosphorylated tau. Because recent …

Alzheimer's disease is the most common form of age-related neurodegenerative dementia.
The disease is characterised by the presence of plaques in the cerebral cortex. The major …