It is a sad fact that despite being almost completely preventable through human
papillomavirus (HPV) vaccination and screening, cervical cancer remains the fourth most …

With the advent of combined immunotherapies, personalized dendritic cell (DC)-based
vaccination could integrate the current standard of care for the treatment of a large variety of …

Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable
development over recent decades. However, this field is currently in a state of flux toward …

Background Human papillomavirus (HPV) infections and associated diseases remain a
serious burden worldwide. It is now clear that HPV serves as the etiological factor and …

With its vast amount of uncharacterized and characterized T cell epitopes available for
activating CD4+ T helper and CD8+ cytotoxic lymphocytes simultaneously, whole tumor …

Although cancer vaccines with defined antigens are commonly used, the use of whole tumor
cell preparations in tumor immunotherapy is a very promising approach and can obviate …

Dendritic cells (DCs) are the most potent antigen-presenting cells, and tumor antigen-loaded
DCs (DC-vaccines) can activate tumor-specific cytotoxic T lymphocytes (CTLs) in lymphatic …

Electroporation (EP) has been used in basic research for the past 25 years to aid in the
transfer of DNA into cells in vitro. EP in vivo enhances transfer of DNA vaccines and …

The identification of human papillomavirus (HPV) as an etiological factor for HPV-associated
malignancies creates the opportunity to control these cancers through vaccination …

In the past decade, we have witnessed important gains in the treatment of ovarian cancer;
however, additional advances are required to reduce mortality. With compelling evidence …