Current state of neuroprotective therapy using antibiotics in human traumatic brain injury and animal models

K Ritter, P Somnuke, L Hu, EV Griemert… - BMC neuroscience, 2024 - Springer
TBI is a leading cause of death and disability in young people and older adults worldwide.
There is no gold standard treatment for TBI besides surgical interventions and symptomatic …

Update in Pediatric Neurocritical Care: What a Neurologist Caring for Critically Ill Children Needs to Know

V Plante, M Basu, JV Gettings, M Luchette… - Seminars in …, 2024 - thieme-connect.com
Currently nearly one-quarter of admissions to pediatric intensive care units (PICUs)
worldwide are for neurocritical care diagnoses that are associated with significant morbidity …

Oral administration of lysozyme protects against injury of ileum via modulating gut microbiota dysbiosis after severe traumatic brain injury

W Yang, C Xi, H Yao, Q Yuan, J Zhang… - Frontiers in Cellular …, 2024 - frontiersin.org
Objective The current study sought to clarify the role of lysozyme-regulated gut microbiota
and explored the potential therapeutic effects of lysozyme on ileum injury induced by severe …

Pharmacotherapy for Traumatic Brain Injury: The Next Generation of Clinical Trials

R Diaz-Arrastia, PM Kochanek - Neurotherapeutics, 2023 - Springer
Traumatic brain injury (TBI) is one of the most common maladies affecting humanity and,
until the late twentieth century, was largely considered beyond the reach of medical science …

All Over the MAP! Cerebral Autoregulation and Optimizing Brain Tissue Oxygenation After Traumatic Brain Injury

PP Patel, T Egodage, MJ Martin - Critical Care Medicine, 2024 - journals.lww.com
Early interventions after acute traumatic brain injury (TBI) provide clinicians an opportunity to
prevent secondary injury and improve neurologic outcomes. One avenue is to optimize brain …