Neonatal hypoxia ischaemia: mechanisms, models, and therapeutic challenges

LJ Millar, L Shi, A Hoerder-Suabedissen… - Frontiers in cellular …, 2017 - frontiersin.org
Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

Long-term outcome after neonatal hypoxic-ischaemic encephalopathy

LS de Vries, MJ Jongmans - Archives of Disease in Childhood-Fetal and …, 2010 - fn.bmj.com
Outcome of full-term infants with neonatal encephalopathy of hypoxic-ischemic origin is
often assessed in infancy or early childhood and data on outcome in childhood and …

Neonatal encephalopathy: an inadequate term for hypoxic–ischemic encephalopathy

JJ Volpe - Annals of neurology, 2012 - Wiley Online Library
Abstract This Point of View article addresses neonatal encephalopathy (NE) presumably
caused by hypoxia–ischemia and the terminology currently in wide use for this disorder. The …

Cerebral magnetic resonance biomarkers in neonatal encephalopathy: a meta-analysis

S Thayyil, M Chandrasekaran, A Taylor… - …, 2010 - publications.aap.org
OBJECTIVE: Accurate prediction of neurodevelopmental outcome in neonatal
encephalopathy (NE) is important for clinical management and to evaluate neuroprotective …

Patterns of neonatal hypoxic–ischaemic brain injury

LS De Vries, F Groenendaal - Neuroradiology, 2010 - Springer
Enormous progress has been made in assessing the neonatal brain, using magnetic
resonance imaging (MRI). In this review, we will describe the use of MRI and proton …

Perinatal asphyxia in the term newborn

R Antonucci, A Porcella, MD Pilloni - Journal of Pediatric and Neonatal …, 2014 - jpnim.com
Despite the important advances in perinatal care in the past decades, asphyxia remains a
severe condition leading to significant mortality and morbidity. Perinatal asphyxia has an …

Congenital heart disease and brain development

PS McQuillen, SP Miller - Annals of the New York Academy of …, 2010 - Wiley Online Library
Brain and heart development occur simultaneously in the human fetus. Given the depth and
complexity of these shared morphogenetic programs, it is perhaps not surprising that …

Fifty years of brain imaging in neonatal encephalopathy following perinatal asphyxia

F Groenendaal, LS de Vries - Pediatric research, 2017 - nature.com
In the past brain imaging of term infants with hypoxic-ischemic encephalopathy (HIE) was
performed with cranial ultrasound (cUS) and computed tomography (CT). Both techniques …

Impaired right ventricular performance is associated with adverse outcome after hypoxic ischemic encephalopathy

RE Giesinger, AI El Shahed, MP Castaldo… - American journal of …, 2019 - atsjournals.org
Rationale: Asphyxiated neonates with hypoxic ischemic encephalopathy (HIE) are at risk of
myocardial dysfunction; however, echocardiography studies are limited and little is known …

Brain injury patterns in hypoglycemia in neonatal encephalopathy

DST Wong, KJ Poskitt, V Chau… - American Journal …, 2013 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Low glucose values are often seen in term infants with NE,
including HIE, yet the contribution of hypoglycemia to the pattern of neurologic injury …