RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Nasopharyngeal carcinoma (NPC) is a particular entity of head neck cancer that is generally
regarded as a genetic disease with diverse intertumor and intratumor heterogeneity. This …

Over the past decade, melanoma has led the field in new cancer treatments, with impressive
gains in on-treatment survival but more modest improvements in overall survival. Melanoma …

Targeting programmed cell death protein ligand 1 (PD-L1) remains one of the most essential
immunotherapies in cancer,. PD-L1 has been detected in the nucleus in multiple …

Advancements in micro‐resolution 3D printers have significantly facilitated the development
of highly complex mass‐producible drug delivery platforms. Conventionally, due to the …

Background Immune exhaustion and senescence are dominant dysfunctional states of
effector T cells and major hurdles for the success of cancer immunotherapy. In the current …

Tumor-infiltrating lymphocytes (TILs) are critical in the elimination of cancer cells, a concept
highlighted by recent advances in cancer immunotherapy. Significant evidence reveals that …

The genetic circuits that allow cancer cells to evade immune killing via epithelial
mesenchymal plasticity remain poorly understood. Here, we showed that mesenchymal-like …

Pigment production is a unique character of melanocytes. Numerous factors are linked with
melanin production, including genetics, ultraviolet radiation (UVR) and inflammation …

Immunotherapy has demonstrated the potential to cure melanoma, while the current
response rate is still unsatisfactory in clinics. Extensive evidence indicates the correlation …