Socio-demographic and clinical predictors of non-response/non-remission in treatment resistant depressed patients: a systematic review

V De Carlo, R Calati, A Serretti - Psychiatry research, 2016 - Elsevier
Up to one third of patients adequately treated for Major Depressive Disorder (MDD) do not
respond to multiple interventions. Many studies investigated predictors in MDD outcome, but …

Early switching strategies in antidepressant non-responders: current evidence and future research directions

PA Kudlow, RS McIntyre, RW Lam - CNS drugs, 2014 - Springer
Studies have found that up to two-thirds of patients with major depressive disorder (MDD) do
not fully respond to the first antidepressant. While switching antidepressants is a common …

抑郁症治疗研究新进展

瞿伟, 谷珊珊 - 第三军医大学学报, 2014 - cqvip.com
抑郁症是一种高患病率, 高疾病负担, 高复发率, 高致残率, 高自杀率的慢性精神疾病. 根据WHO
最新报告, 预计到2020 年, 抑郁症将成为导致人类死亡和致残的第二大类疾病. 自20 世纪80 …

A new prediction model for evaluating treatment-resistant depression

A Kautzky, P Baldinger-Melich, GS Kranz… - The Journal of clinical …, 2017 - psychiatrist.com
Objective: Despite a broad arsenal of antidepressants, about a third of patients suffering
from major depressive disorder (MDD) do not respond sufficiently to adequate treatment …

Omega-3 polyunsaturated fatty acids for major depressive disorder

KP Su, SM Wang, CU Pae - Expert Opinion on Investigational …, 2013 - Taylor & Francis
Introduction: Omega-3 polyunsaturated fatty acids (omega-3 PUFAs) are not synthesized by
the human body; they must be derived from dietary sources and they have been known to be …

The effectiveness of prefrontal theta cordance and early reduction of depressive symptoms in the prediction of antidepressant treatment outcome in patients with …

M Bares, T Novak, M Kopecek, M Brunovsky… - European archives of …, 2015 - Springer
Current studies suggest that an early improvement of depressive symptoms and the
reduction of prefrontal theta cordance value predict the subsequent response to …

The comparison of effectiveness of various potential predictors of response to treatment with SSRIs in patients with depressive disorder

M Bares, T Novak, M Brunovsky… - The Journal of …, 2017 - journals.lww.com
The substantial non-response rate in depressive patients indicates a continuing need to
identify predictors of treatment outcome. The aim of this 6-week, open-label study was (1) to …

Is it worth assessing progress as early as week 2 to adapt antidepressive treatment strategy? Results from a study on agomelatine and a global meta-analysis

P Gorwood, F Bayle, G Vaiva, P Courtet… - European …, 2013 - cambridge.org
Context: A delay of 4–8 weeks before modifying the prescribed antidepressant treatment is
usually proposed when incomplete treatment response is observed. A number of studies …

Hamilton depression rating subscales to predict antidepressant treatment outcome in the early course of treatment

I Helmreich, S Wagner, J König, R Kohnen… - Journal of affective …, 2015 - Elsevier
Background Hamilton depression rating scale (HAMD) subscales provide an economic
alternative for the full scale; however, their ability to detect onset of improvement in the early …

Clinical issues in use of atypical antipsychotics for depressed patients

CU Pae, AA Patkar - CNS drugs, 2013 - Springer
Major depressive disorder (MDD) is a chronic, recurrent mental disease that causes serious
disability. Because currently available antidepressants have limited efficacy with respect to …