Regulatory T cells (Treg cells) are key players in ensuring a peaceful coexistence with
microorganisms and food antigens at intestinal borders. Startling new information has …

The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Lipid metabolism plays a major role in the regulation of the immune system. Exogenous
(dietary and microbial-derived) and endogenous (non-microbial-derived) lipids play a direct …

The gastrointestinal tract is home to the largest microbial population in the human body. The
gut microbiota plays significant roles in the development of the gut immune system and has …

The intricate interplay between gut microbes and the onset of experimental autoimmune
encephalomyelitis (EAE) remains poorly understood. Here, we uncover remarkable …

The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …

The incomplete removal of T cells that are reactive against self-proteins during their
differentiation in the thymus requires mechanisms of tolerance that prevent their effector …

Recent strategies to combine chemoradiation with immunotherapy to treat locally advanced
lung cancer have improved five-year survival outcomes. However, collateral toxicity to …

Regulatory T cells (Tregs) control immune responses and are essential to maintain immune
homeostasis and self-tolerance. Hence, it is no coincidence that autoimmune and chronic …

During an immune response, the duration of T cell residence in lymphoid and non‐lymphoid
tissues likely affects T cell activation, differentiation, and memory development. The factors …