As a major site of glucose uptake following a meal, skeletal muscle has an important role in
whole-body glucose metabolism. Evidence in humans and animal models of insulin …

Glucose is an important nutrient that dictates the development, fertility and lifespan of all
organisms. In humans, a deficit in its homeostatic control might lead to hyperglucemia and …

High-fat diet (HFD) feeding in rodents has become an essential tool to critically analyze and
study the pathological effects of obesity, including mitochondrial dysfunction and insulin …

Perivascular adipose tissue (PVAT) undergoes functional changes in obesity. Increased
oxidative stress is a central mechanism whereby obesity induces loss of the anticontractile …

Imbalanced mitochondrial dynamics in pancreatic β-cells contributes to β-cell dysfunction in
diabetes; however, the molecular mechanisms underlying mitochondrial dynamics in the …

PURPOSE: The purpose of this study was to investigate the effect of polyhexamethylene
biguanide (PHMB) solution as a wound cleanser on bacterial load and bacterial biofilm in …

The effects of weight loss produced by increased energy expenditure on measures of
oxidative stress and mitochondrial damage have not been investigated in the hypothalamus …

Previous studies have highlighted the positive effects of Estradiol (E2) replacement therapy
and physical exercise on skeletal muscle during menopause. However, the comparison …

Background The genetic profile that is needed to define an endurance athlete has been
studied during recent years. The main objective of this work is to approach for the first time …

Cognitive reserve has been proposed to account for different responses to brain damage or
pathology. Factors implicated to influence cognitive reserve include cognitive engagement …