Application of ligature-induced periodontitis in mice to explore the molecular mechanism of periodontal disease

P Lin, H Niimi, Y Ohsugi, Y Tsuchiya… - International journal of …, 2021 - mdpi.com
Periodontitis is an inflammatory disease characterized by the destruction of the
periodontium. In the last decade, a new murine model of periodontitis has been widely used …

The role of the host—Neutrophil biology

ILC Chapple, J Hirschfeld, A Kantarci… - Periodontology …, 2023 - Wiley Online Library
Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with
lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial …

Immune senescence and periodontitis: From mechanism to therapy

J Liu, R Dan, X Zhou, J Xiang, J Wang… - Journal of Leukocyte …, 2022 - academic.oup.com
Periodontitis is one of the most prevalent infectious inflammatory diseases, characterized by
irreversible destruction of the supporting tissues of teeth, which is correlated with a greater …

Interaction between immuno-stem dual lineages in jaw bone formation and injury repair

Z Liu, X Luo, R Xu - Frontiers in Cell and Developmental Biology, 2024 - frontiersin.org
The jawbone, a unique structure in the human body, undergoes faster remodeling than other
bones due to the presence of stem cells and its distinct immune microenvironment. Long …

Interactions of B-lymphocytes and bone cells in health and disease

D Grčević, A Sanjay, J Lorenzo - Bone, 2023 - Elsevier
Bone remodeling occurs through the interactions of three major cell lineages, osteoblasts,
which mediate bone formation, osteocytes, which derive from osteoblasts, sense mechanical …

Identification of hub genes related to immune cell infiltration in periodontitis using integrated bioinformatic analysis

X Gao, C Jiang, S Yao, L Ma, X Wang… - Journal of Periodontal …, 2022 - Wiley Online Library
Background and objective Periodontitis is an inflammatory disease of the periodontium.
However, the hub genes in periodontitis and their correlation with immune cells are not …

An update on periodontal inflammation and bone loss

M Zhang, Y Liu, H Afzali, DT Graves - Frontiers in Immunology, 2024 - frontiersin.org
Periodontal disease is a chronic inflammatory condition that affects the supporting structures
of the teeth, including the periodontal ligament and alveolar bone. Periodontal disease is …

[HTML][HTML] Nano-emulsion of mangosteen rind extract in a mucoadhesive patch for periodontitis regenerative treatment: An in vivo study

MA Aljuanid, HR Qaid, DM Lashari, RD Ridwan… - Journal of Taibah …, 2022 - Elsevier
Objective To investigate the therapeutic potential of nano-emulsion of mangosteen rind
extract in a mucoadhesive gingival patch on periodontitis, and its effect on tumor necrosis …

Regulatory B cells induced by interleukin‐35 inhibit inflammation and alveolar bone resorption in ligature‐induced periodontitis

S Li, L Su, Q Luan, G Liu, W Zeng… - Journal of …, 2023 - Wiley Online Library
Abstract Background Regulatory B cells (Bregs) have been reported to suppress immune
responses and alveolar bone loss in murine periodontitis models. These cells could be …

B-cell deficiency exacerbates inflammation and bone loss in ligature-induced experimental periodontitis in mice

W Zeng, G Liu, Q Luan, C Yang, S Li… - Journal of Inflammation …, 2021 - Taylor & Francis
Objective Periodontitis, one of the most prevalent chronic oral infectious diseases in
humans, is induced by the breakdown in the balance between the biofilm and host immune …