Human papillomaviruses as infectious agents in gynecological cancers. oncogenic properties of viral proteins

DA Haręża, JR Wilczyński, E Paradowska - International journal of …, 2022 - mdpi.com
Human papillomaviruses (HPVs), which belong to the Papillomaviridae family, constitute a
group of small nonenveloped double-stranded DNA viruses. HPV has a small genome that …

Pathways of vulvar intraepithelial neoplasia and squamous cell carcinoma

M Del Pino, L Rodriguez‐Carunchio, J Ordi - Histopathology, 2013 - Wiley Online Library
Vulvar squamous cell carcinoma (VSCC) accounts for> 90% of the malignant tumours of the
vulva. Most VSCC s originate in intraepithelial lesions, named vulvar intraepithelial …

Prevalence of human papillomavirus DNA and p16INK4a positivity in vulvar cancer and vulvar intraepithelial neoplasia: a systematic review and meta-analysis

Z Li, P Liu, Z Wang, Z Zhang, Z Chen, R Chu… - The Lancet …, 2023 - thelancet.com
Summary Background Human papillomavirus (HPV) DNA and p16 INK4a positivity have
crucial roles in the pathogenesis of vulvar cancer and vulvar intraepithelial neoplasia. We …

Vaccination against oncoproteins of HPV16 for noninvasive vulvar/vaginal lesions: lesion clearance is related to the strength of the T-cell response

MIE van Poelgeest, MJP Welters, R Vermeij… - Clinical Cancer …, 2016 - AACR
Purpose: Therapeutic vaccination with human papillomavirus type 16 (HPV16) E6 and E7
synthetic long peptides (SLP) is effective against HPV16-induced high-grade vulvar and …

[HTML][HTML] Prevalence of human papillomavirus DNA in different histological subtypes of cervical adenocarcinoma

EC Pirog, B Kleter, S Olgac, P Bobkiewicz… - The American journal of …, 2000 - Elsevier
The prevalence of human papilloma virus (HPV) DNA in different histological subtypes of
cervical adenocarcinoma and related tumors was examined using formalin-fixed, paraffin …

Prevalence and type distribution of human papillomavirus in squamous cell carcinoma and intraepithelial neoplasia of the vulva

MT Faber, FL Sand, V Albieri, B Norrild… - … journal of cancer, 2017 - Wiley Online Library
In this updated systematic review and meta‐analysis, we estimate the pooled prevalence of
human papillomavirus (HPV) DNA and HPV type distribution in squamous cell carcinoma of …

Phase II trial of imiquimod and HPV therapeutic vaccination in patients with vulval intraepithelial neoplasia

S Daayana, E Elkord, U Winters, M Pawlita… - British journal of …, 2010 - nature.com
Background: Vulval intraepithelial neoplasia (VIN) is a premalignant condition, which is
frequently associated with type HPV16 infection, and multifocal disease has high rates of …

Currently approved prophylactic HPV vaccines

DM Harper - Expert review of vaccines, 2009 - Taylor & Francis
Cervarix® and Gardasil® are two prophylactic HPV vaccines designed primarily for cervical
cancer prevention. Cervarix is effective against HPV-16,-18,-31,-33 and-45, the five most …

Human papillomavirus prevalence in invasive penile cancer and association with clinical outcome

RS Djajadiningrat, ES Jordanova, BK Kroon… - The Journal of …, 2015 - auajournals.org
Purpose: The incidence of penile cancer is increasing, and is suggested to be explained by
changes in sexual practice and increased exposure of men to sexually transmitted high risk …

Human papillomavirus vaccines: current status and future prospects

SM Garland, JS Smith - Drugs, 2010 - Springer
Worldwide, cervical cancer is the second most common cancer of women. Less-developed
countries bear the greatest burden in terms of morbidity and mortality, largely due to the lack …