Infectious diseases continue to pose an imminent threat to global public health, leading to
high numbers of deaths every year and disproportionately impacting developing countries …

The early detection of infectious diseases and microorganisms is critical for effective disease
treatment, control, and prevention. Currently, nucleic acid testing and antigen–antibody …

CRISPR-Cas-based diagnostics have the potential to elevate nucleic acid detection.
CRISPR-Cas systems can be combined with a pre-amplification step in a one-pot reaction to …

Mpox is caused by a zoonotic virus belonging to the Orthopoxvirus genus and the
Poxviridae family. In this study, we develop a recombinase polymerase amplification (RPA) …

Pathogen-specific point-of-care (PoC) diagnostic tests have become an important need in
the fight against infectious diseases and epidemics in recent years. PoC diagnostic tests are …

Background CRISPR-Cas based diagnostic assays provide a portable solution which
bridges the benefits of qRT-PCR and serological assays in terms of portability, specificity …

CRISPR is an acquired immune system found in prokaryotes that can accurately recognize
and cleave foreign nucleic acids, and has been widely explored for gene editing and …

Emerging infectious diseases (EIDs) pose an increasingly significant global burden, driven
by urbanization, population explosion, global travel, changes in human behavior, and …

The combination of clustered regularly interspaced short palindromic repeats (CRISPR) and
its associated Cas protein is an effective gene-editing instrument. Among them, the CRISPR …

Integrating artificial intelligence with SARS-CoV-2 diagnostics can help in the timely
execution of pandemic control and monitoring plans. To improve the efficiency of the …