SARS-CoV-2 (COVID-19) as a possible risk factor for neurodevelopmental disorders

H Dubey, RK Sharma, S Krishnan… - Frontiers in …, 2022 - frontiersin.org
Pregnant women constitute one of the most vulnerable populations to be affected by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the cause of coronavirus …

Let's get physical: flavivirus-host protein–protein interactions in replication and pathogenesis

AT Fishburn, OH Pham, MW Kenaston… - Frontiers in …, 2022 - frontiersin.org
Flaviviruses comprise a genus of viruses that pose a significant burden on human health
worldwide. Transmission by both mosquito and tick vectors, and broad host tropism …

The Epidermal Growth Factor Receptor Is a Relevant Host Factor in the Early Stages of The Zika Virus Life Cycle In Vitro

C Sabino, D Bender, ML Herrlein, E Hildt - Journal of virology, 2021 - Am Soc Microbiol
Zika virus (ZIKV) is a flavivirus that is well known for the epidemic in the Americas in 2015
and 2016 in which microcephaly in newborns and other neurological complications were …

The interplay between brain vascular calcification and microglia

U Maheshwari, SF Huang, S Sridhar… - Frontiers in Aging …, 2022 - frontiersin.org
Vascular calcifications are characterized by the ectopic deposition of calcium and phosphate
in the vascular lumen or wall. They are a common finding in computed tomography scans or …

RIG-I and MDA5 are modulated by bone morphogenetic protein (BMP6) and are essential for restricting Zika virus infection in human Sertoli cells

B Jiyarom, S Giannakopoulos, DP Strange… - Frontiers in …, 2023 - frontiersin.org
Sexual transmission of Zika virus (ZIKV) is associated with virus persistence in the testes
and shedding in the seminal fluid for months after recovery. We previously demonstrated …

[HTML][HTML] Insights into the structure, functional perspective, and pathogenesis of ZIKV: an updated review

EA Bhat, T Ali, N Sajjad, P Bron - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Zika virus (ZIKV) poses a serious threat to the entire world. The rapid spread of ZIKV and
recent outbreaks since 2007 have caused worldwide concern about the virus. Diagnosis is …

Mechanistic insights into bone remodelling dysregulation by human viral pathogens

CCS Caetano, T Azamor, NM Meyer… - Nature …, 2024 - nature.com
Bone-related diseases (osteopathologies) associated with human virus infections have
increased around the globe. Recent findings have highlighted the intricate interplay …

Zika Virus and Neuropathogenesis: The Unanswered Question of Which Strain Is More Prone to Causing Microcephaly and Other Neurological Defects

EL King, N Irigoyen - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Despite being perceived to be a relatively innocuous pathogen during its circulation in Africa
in the 20th century, consequent outbreaks in French Polynesia and Latin America revealed …

Modulation of cellular machineries by Zika virus‐encoded proteins

S Dong, MZX Xiao, Q Liang - Journal of Medical Virology, 2023 - Wiley Online Library
The strain of Zika virus (ZIKV) that circulated during the 2015 epidemic in Brazil has been
associated with more than 2000 cases of microcephaly from September 2015 through …

[HTML][HTML] Ataluren prevented bone loss induced by ovariectomy and aging in mice through the BMP-SMAD signaling pathway

L Zeng, R Gu, W Li, Y Shao, Y Zhu, Z Xie, H Liu… - Biomedicine & …, 2023 - Elsevier
Both estrogen deficiency and aging may lead to osteoporosis. Developing novel drugs for
treating osteoporosis is a popular research direction. We screened several potential …