Chronic inflammation has emerged as one of the hallmarks of cancer. Inflammation also
plays a pivotal role in modulating radiation responsiveness of tumors. As discussed in this …

Hypoxic microenvironments frequently exist in many solid tumours with oxygen levels
fluctuating temporally and spatially from normoxia to hypoxia. The response to hypoxia in …

Hypoxic radioresistance plays a critical role in the radiotherapy of cancer and adversely
impacts prognosis and treatment response. This prospective study investigated the …

Despite recent advances in current treatment approaches, the prognosis of highgrade
gliomas is still poor [1]. One of the important mechanisms and a common feature of high …

Recent findings suggest that hypoxia of the tumor microenvironment contributes to immune
escape from natural killer (NK) cell-mediated cytotoxicity. Heat shock protein 70 (Hsp70) and …

Background Ionizing irradiation is a commonly accepted treatment modality for lung cancer
patients. However, the clinical outcome is hampered by normal tissue toxicity and tumor …

Betel nut chewing is associated with oral cavity cancer. Radiotherapy is one of the
therapeutic approaches. Here, we used miR-17-5p antisense oligonucleotides (AS-ODNs) …

Background and purpose: Betel nut chewing is associated with oral cavity cancer in Taiwan.
OC3 is an oral carcinoma cell line that was established from cells collected from a long-term …

Tumor hypoxia is a major problem in radiation therapy of solid tumors because of the
radiosensitizing effect of oxygen. Nitroimidazole-containing compounds are oxygen …

摘要目的: 探讨高氧对雄激素敏感的前列腺癌细胞移植瘤生长及其缺氧诱导因子-1
琢表达的影响. 方法: 将前列腺癌前列腺淋巴结癌(LNCaP) 细胞接种于36 只Foxn1 …