Tissue fibrosis induced by radiotherapy: current understanding of the molecular mechanisms, diagnosis and therapeutic advances
Z Yu, C Xu, B Song, S Zhang, C Chen, C Li… - Journal of Translational …, 2023 - Springer
Cancer remains the leading cause of death around the world. In cancer treatment, over 50%
of cancer patients receive radiotherapy alone or in multimodal combinations with other …
of cancer patients receive radiotherapy alone or in multimodal combinations with other …
Glycolysis Reprogramming in Idiopathic Pulmonary Fibrosis: Unveiling the Mystery of Lactate in the Lung
P Yan, J Liu, Z Li, J Wang, Z Zhu, L Wang… - International Journal of …, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease characterized
by excessive deposition of fibrotic connective tissue in the lungs. Emerging evidence …
by excessive deposition of fibrotic connective tissue in the lungs. Emerging evidence …
PI3K/mTOR inhibitors promote G6PD autophagic degradation and exacerbate oxidative stress damage to radiosensitize small cell lung cancer
H Deng, Y Chen, L Wang, Y Zhang, Q Hang, P Li… - Cell Death & …, 2023 - nature.com
Our previous study revealed that PI3K/AKT/mTOR signaling was associated with SCLC
radioresistance. SBC2 cells were used as primary radioresistance models, while H446 cells …
radioresistance. SBC2 cells were used as primary radioresistance models, while H446 cells …
[HTML][HTML] ACT001 Ameliorates ionizing radiation-induced lung injury by inhibiting NLRP3 inflammasome pathway
H Luo, X Liu, H Liu, Y Wang, K Xu, J Li, M Liu… - Biomedicine & …, 2023 - Elsevier
Radiotherapy is a prevalent treatment modality for thoracic tumors; however, it can lead to
radiation-induced lung injury (RILI), which currently lacks effective interventions. ACT001, a …
radiation-induced lung injury (RILI), which currently lacks effective interventions. ACT001, a …
Cell type-specific roles of NLRP3, inflammasome-dependent and-independent, in host defense, sterile necroinflammation, tissue repair, and fibrosis
TSB Honda, J Ku, HJ Anders - Frontiers in Immunology, 2023 - frontiersin.org
The NLRP3 inflammasome transforms a wide variety of infectious and non-infectious danger
signals that activate pro-inflammatory caspases, which promote the secretion of IL-1β and IL …
signals that activate pro-inflammatory caspases, which promote the secretion of IL-1β and IL …
Pyroptotic cell death: an emerging therapeutic opportunity for radiotherapy
H Li, T Yang, J Zhang, K Xue, X Ma, B Yu, X Jin - Cell Death Discovery, 2024 - nature.com
Pyroptotic cell death, an inflammatory form of programmed cell death (PCD), is emerging as
a potential therapeutic opportunity for radiotherapy (RT). RT is commonly used for cancer …
a potential therapeutic opportunity for radiotherapy (RT). RT is commonly used for cancer …
[HTML][HTML] Nintedanib Mitigates Radiation-Induced Pulmonary Fibrosis by Suppressing Epithelial Cell Inflammatory Response and Inhibiting Fibroblast-to-Myofibroblast …
J Tu, X Chen, C Li, C Liu, Y Huang… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Radiation-induced pulmonary fibrosis (RIPF) represents a serious complication observed in
individuals undergoing thoracic radiation therapy. Currently, effective interventions for RIPF …
individuals undergoing thoracic radiation therapy. Currently, effective interventions for RIPF …
Tolerogenic dendritic cells in radiation-induced lung injury
B Liu, Y Wang, G Han, M Zhu - Frontiers in Immunology, 2024 - frontiersin.org
Radiation-induced lung injury is a common complication associated with radiotherapy. It is
characterized by early-stage radiation pneumonia and subsequent radiation pulmonary …
characterized by early-stage radiation pneumonia and subsequent radiation pulmonary …
NXC736 Attenuates Radiation-Induced Lung Fibrosis via Regulating NLRP3/IL-1β Signaling Pathway
SY Kim, S Park, R Cui, H Lee, H Choi… - International journal of …, 2023 - mdpi.com
Radiation-induced lung fibrosis (RILF) is a common complication of radiotherapy in lung
cancer. However, to date no effective treatment has been developed for this condition …
cancer. However, to date no effective treatment has been developed for this condition …
The Radioprotective Effect of LBP on Neurogenesis and Cognition after Acute Radiation Exposure
G Yin, Q Wang, T Lv, Y Liu, X Peng… - Current …, 2024 - ingentaconnect.com
Background: Radiation exposure has been linked to the development of brain damage and
cognitive impairment, but the protective effect and mechanism of Lycium barbarum pills …
cognitive impairment, but the protective effect and mechanism of Lycium barbarum pills …