Bone and renal metabolism are regulated by common factors and there is extensive cross-
talk between these organs (the 'renal-bone-axis'). Ageing is associated with physiological …

Hyperphosphatemia is a well-known feature of advanced chronic kidney disease (CKD) and
a major risk factor for cardiovascular events in patients with CKD, inducing calcium …

The hypothesis that dietary inclusion of microbial phytase improves apparent calcium (Ca)
digestibility thereby allowing a lower dietary Ca inclusion without compromising growth …

Background: Kidney diseases are a prevalent health problem worldwide. Although
substantial progress has been made in understanding the pathophysiology of kidney …

Background Kidney stones are frequent in industrialized countries with a lifetime risk of 10 to
15%. A high percentage of individuals experience recurrence. Calcium-containing stones …

receptor antagonists (MRAs), such as spironolactone and eplerenone, are used in the
treatment of heart failure and hypertension. Finerenone is a new, nonsteroidal MRA that was …

Background and purpose Fibroblast growth factor 23 (FGF23) is an osteogenic hormone
associated with chronic kidney disease and is an emerging risk factor for several …

Patients with end-stage kidney disease (ESKD) suf-fer from exceptionally high rates of heart
disease and poor responsiveness to treatments that are of proven benefit in the general …

Introduction A negative association between C-terminal fibroblast growth factor 23 (cFGF23)
and hemoglobin (Hb) levels has been reported in patients with predialysis chronic kidney …

Calcium and phosphorus metabolism involves in patients with chronic kidney disease-
mineral and bone disorder (CKD-MBD). Sclerostin and bone morphogenetic protein-7 (BMP …