Genomic and personalized medicine: foundations and applications
GS Ginsburg, HF Willard - Translational research, 2009 - Elsevier
The last decade has witnessed a steady embrace of genomic and personalized medicine by
senior government officials, industry leadership, health care providers, and the public …
senior government officials, industry leadership, health care providers, and the public …
Machine learning applications in drug development
Due to the huge amount of biological and medical data available today, along with well-
established machine learning algorithms, the design of largely automated drug development …
established machine learning algorithms, the design of largely automated drug development …
[HTML][HTML] Grand challenges in clinical decision support
There is a pressing need for high-quality, effective means of designing, developing,
presenting, implementing, evaluating, and maintaining all types of clinical decision support …
presenting, implementing, evaluating, and maintaining all types of clinical decision support …
High-dimensional sparse factor modeling: applications in gene expression genomics
CM Carvalho, J Chang, JE Lucas… - Journal of the …, 2008 - Taylor & Francis
We describe studies in molecular profiling and biological pathway analysis that use sparse
latent factor and regression models for microarray gene expression data. We discuss breast …
latent factor and regression models for microarray gene expression data. We discuss breast …
Taking gene-expression profiling to the clinic: when will molecular signatures become relevant to patient care?
C Sotiriou, MJ Piccart - Nature reviews cancer, 2007 - nature.com
The advent of microarray technology has enabled scientists to simultaneously investigate
the expression of thousands of genes. Gene-expression profiling studies have provided a …
the expression of thousands of genes. Gene-expression profiling studies have provided a …
Feature selection methods and genomic big data: a systematic review
In the era of accelerating growth of genomic data, feature-selection techniques are believed
to become a game changer that can help substantially reduce the complexity of the data …
to become a game changer that can help substantially reduce the complexity of the data …
Bayesian methods in bioinformatics and computational systems biology
DJ Wilkinson - Briefings in bioinformatics, 2007 - academic.oup.com
Bayesian methods are valuable, inter alia, whenever there is a need to extract information
from data that are uncertain or subject to any kind of error or noise (including measurement …
from data that are uncertain or subject to any kind of error or noise (including measurement …
[图书][B] Healthcare data analytics
CK Reddy, CC Aggarwal - 2015 - books.google.com
Supplying a comprehensive overview of healthcare analytics research, Healthcare Data
Analytics provides an understanding of the analytical techniques currently available to solve …
Analytics provides an understanding of the analytical techniques currently available to solve …
Emergence of drug discovery in machine learning
SN Roy, S Mishra, SM Yusof - Technical advancements of machine …, 2021 - Springer
The discovery of drugs and its pipelines formulation is tough, long, and depend on various
factors. Machine Learning comes as a savior to this field and supplies different tools and …
factors. Machine Learning comes as a savior to this field and supplies different tools and …
A cryptographic approach to securely share and query genomic sequences
M Kantarcioglu, W Jiang, Y Liu… - IEEE Transactions on …, 2008 - ieeexplore.ieee.org
To support large-scale biomedical research projects, organizations need to share person-
specific genomic sequences without violating the privacy of their data subjects. In the past …
specific genomic sequences without violating the privacy of their data subjects. In the past …