Role of Innate Immunity in Allergic Contact Dermatitis: An Update
HL Yamaguchi, Y Yamaguchi, E Peeva - International Journal of …, 2023 - mdpi.com
Our understanding of allergic contact dermatitis mechanisms has progressed over the past
decade. Innate immune cells that are involved in the pathogenesis of allergic contact …
decade. Innate immune cells that are involved in the pathogenesis of allergic contact …
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease
Eosinophils are bone marrow-derived granulocytes that are traditionally associated with
type 2 immune responses, such as those that occur during parasite infections and allergy …
type 2 immune responses, such as those that occur during parasite infections and allergy …
Nutrient-derived signals regulate eosinophil adaptation to the small intestine
V I. Kutyavin, LL Korn… - Proceedings of the …, 2024 - National Acad Sciences
Eosinophils are well recognized as effector cells of type 2 immunity, yet they also
accumulate in many tissues under homeostatic conditions. However, the processes that …
accumulate in many tissues under homeostatic conditions. However, the processes that …
CCR3-dependent eosinophil recruitment is regulated by sialyltransferase ST3Gal-IV
R Immler, K Nussbaumer, A Doerner… - Proceedings of the …, 2024 - National Acad Sciences
Eosinophil recruitment is a pathological hallmark of many allergic and helminthic diseases.
Here, we investigated chemokine receptor CCR3-induced eosinophil recruitment in …
Here, we investigated chemokine receptor CCR3-induced eosinophil recruitment in …
Generation and repair of thymic epithelial cells
In the vertebrate immune system, thymus stromal microenvironments support the generation
of αβT cells from immature thymocytes. Thymic epithelial cells are of particular importance …
of αβT cells from immature thymocytes. Thymic epithelial cells are of particular importance …
Stromal cell and B cell dialogue potentiates IL-33-enriched lymphoid niches to support eosinophil recruitment and function during type 2 immunity
Eosinophils are involved in host protection against multicellular organisms. However, their
recruitment to the mesenteric lymph node (mLN) during type 2 immunity is understudied. Our …
recruitment to the mesenteric lymph node (mLN) during type 2 immunity is understudied. Our …
[HTML][HTML] Unveiling multifaceted roles of myeloid innate immune cells in the pathogenesis of psoriasis
S Park, J Jang, HJ Kim, YJ Jung - Molecular Aspects of Medicine, 2024 - Elsevier
Psoriasis is a chronic inflammatory skin disease occurring worldwide. Initially viewed as a
keratinocyte disorder, psoriasis is now recognized to involve a complex interplay between …
keratinocyte disorder, psoriasis is now recognized to involve a complex interplay between …
Eosinophil expression of triggering receptor expressed on myeloid cells 1 (TREM-1) restricts type 2 lung inflammation
JL Bowen, K Keck, S Baruah, KH Nguyen… - Journal of Leukocyte …, 2024 - academic.oup.com
Asthma affects 25 million Americans, and recent advances in treatment are effective for only
a portion of severe asthma patients. TREM-1, an innate receptor that canonically amplifies …
a portion of severe asthma patients. TREM-1, an innate receptor that canonically amplifies …
Eosinophils as Modulators of Host Defense during Parasitic, Fungal, Bacterial, and Viral Infections
PH Gazzinelli-Guimaraes, SM Jones… - Journal of Leukocyte …, 2024 - academic.oup.com
Eosinophils, traditionally associated as central innate effector cells with type-2 immunity
during allergic and helminth parasitic diseases, have recently been revealed to have …
during allergic and helminth parasitic diseases, have recently been revealed to have …
Eosinophils as drivers of bacterial immunomodulation and persistence
KM Parrish, MC Gestal - Infection and Immunity, 2024 - journals.asm.org
Traditionally, eosinophils have been linked to parasitic infections and pathological disease
states. However, emerging literature has unveiled a more nuanced and intricate role for …
states. However, emerging literature has unveiled a more nuanced and intricate role for …