[HTML][HTML] Fetal programming and cardiovascular pathology

BT Alexander, JH Dasinger… - Comprehensive Physiology, 2015 - ncbi.nlm.nih.gov
Low birth weight serves as a crude proxy for impaired growth during fetal life and indicates a
failure for the fetus to achieve its full growth potential. Low birth weight can occur in …

Cardiovascular risk factors in offspring exposed to gestational diabetes mellitus in utero: systematic review and meta-analysis

MM Pathirana, ZS Lassi, CT Roberts… - … origins of health and …, 2020 - cambridge.org
Gestational diabetes mellitus (GDM) is a pregnancy complication that affects one in seven
pregnancies. Emerging evidence demonstrates that children born of pregnancies …

Maternal obesity and the developmental programming of hypertension: a role for leptin

PD Taylor, AM Samuelsson, L Poston - Acta physiologica, 2014 - Wiley Online Library
Mother–child cohort studies have established that both pre‐pregnancy body mass index
(BMI) and gestational weight gain are independently associated with cardio‐metabolic risk …

Childhood health consequences of maternal obesity during pregnancy: a narrative review

R Gaillard, S Santos, L Duijts, JF Felix - Annals of Nutrition and …, 2017 - karger.com
Background: Obesity is a major public health problem among women of reproductive age. In
a narrative review, we examined the influence of maternal obesity during pregnancy on fetal …

Central nervous system neuroplasticity and the sensitization of hypertension

AK Johnson, B Xue - Nature Reviews Nephrology, 2018 - nature.com
The causes of essential hypertension remain an enigma. Interactions between genetic and
external factors are generally recognized to act as aetiological mechanisms that trigger the …

Impact of maternal obesity on fetal programming of cardiovascular disease

VHJ Roberts, AE Frias, KL Grove - Physiology, 2015 - journals.physiology.org
The in utero environment is a key determinant of long-term health outcomes; poor maternal
metabolic state and placental insufficiency are strongly associated with these long-term …

Programming by maternal obesity: a pathway to poor cardiometabolic health in the offspring

I Inzani, SE Ozanne - Proceedings of the Nutrition Society, 2022 - cambridge.org
There is an ever increasing prevalence of maternal obesity worldwide such that in many
populations over half of women enter pregnancy either overweight or obese. This review …

Lifestyle intervention in obese pregnancy and cardiac remodelling in 3-year olds: children of the UPBEAT RCT

PD Taylor, H Gu, H Saunders, F Fiori… - International Journal of …, 2022 - nature.com
Abstract Background/Objectives Obesity in pregnancy has been associated with increased
childhood cardiometabolic risk and reduced life expectancy. The UK UPBEAT multicentre …

Maternal overnutrition elevates offspring's blood pressure—A systematic review and meta‐analysis

S Eitmann, P Mátrai, D Németh, P Hegyi… - Paediatric and …, 2022 - Wiley Online Library
Background Maternal overnutrition during pregnancy predisposes the offspring to
cardiometabolic diseases. Objectives This systematic review and meta‐analysis aimed to …

Association between maternal prepregnancy body mass index and anthropometric parameters, blood pressure, and retinal microvasculature in children age 4 to 6 …

B Cox, LJ Luyten, Y Dockx, E Provost… - JAMA network …, 2020 - jamanetwork.com
Importance Maternal prepregnancy body mass index (BMI; calculated as weight in kilograms
divided by height in meters squared) has previously been associated with offspring …