Endothelial dysfunction in hypertension: current concepts and clinical implications

G Gallo, M Volpe, C Savoia - Frontiers in medicine, 2022 - frontiersin.org
Endothelium plays a fundamental role in the cardiovascular system, forming an interface
between blood and adjacent tissues by regulating the vascular tone through the synthesis of …

New directions in therapeutic angiogenesis and arteriogenesis in peripheral arterial disease

BH Annex, JP Cooke - Circulation research, 2021 - Am Heart Assoc
The prevalence of peripheral arterial disease (PAD) in the United States exceeds 10 million
people, and PAD is a significant cause of morbidity and mortality across the globe. PAD is …

Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives

W Poller, S Dimmeler, S Heymans, T Zeller… - European heart …, 2018 - academic.oup.com
Recent research has demonstrated that the non-coding genome plays a key role in genetic
programming and gene regulation during development as well as in health and …

H19 induces abdominal aortic aneurysm development and progression

DY Li, A Busch, H Jin, E Chernogubova, J Pelisek… - Circulation, 2018 - Am Heart Assoc
Background: Long noncoding RNAs have emerged as critical molecular regulators in
various biological processes and diseases. Here we sought to identify and functionally …

Long non-coding RNA H19 regulates glioma angiogenesis and the biological behavior of glioma-associated endothelial cells by inhibiting microRNA-29a

P Jia, H Cai, X Liu, J Chen, J Ma, P Wang, Y Liu… - Cancer letters, 2016 - Elsevier
Long non-coding RNAs (lncRNAs) play crucial roles in the development and progression of
glioma. Previous studies indicated that lncRNA H19 regulated tumor carcinogenesis …

LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner

WT Wang, H Ye, PP Wei, BW Han, B He… - Journal of hematology & …, 2016 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) are known to play important roles in
different cell contexts, including cancers. However, little is known about lncRNAs in …

[HTML][HTML] Angio-LncRs: LncRNAs that regulate angiogenesis and vascular disease

B Yu, S Wang - Theranostics, 2018 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) represent a large subgroup of RNAs that are longer than
200 nucleotides and have no apparent protein coding potential. They have diverse functions …

The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2

P Neumann, N Jaé, A Knau, SF Glaser… - Nature …, 2018 - nature.com
Impaired or excessive growth of endothelial cells contributes to several diseases. However,
the functional involvement of regulatory long non-coding RNAs in these processes is not …

Long noncoding RNA dysregulation in ischemic heart failure

S Greco, G Zaccagnini, A Perfetti, P Fuschi… - Journal of translational …, 2016 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) are non-protein coding transcripts
regulating a variety of physiological and pathological functions. However, their implication in …

LncRNAs in vascular biology and disease

V Simion, S Haemmig, MW Feinberg - Vascular pharmacology, 2019 - Elsevier
Accumulating studies indicate that long non-coding RNAs (lncRNAs) play important roles in
the regulation of diverse biological processes involved in homeostatic control of the vessel …