Near-infrared metal agents assisting precision medicine: from strategic design to bioimaging and therapeutic applications

C Li, Y Pang, Y Xu, M Lu, L Tu, Q Li… - Chemical Society …, 2023 - pubs.rsc.org
Metal agents have made incredible strides in preclinical research and clinical applications in
recent years, but their short emission/absorption wavelengths continue to be a barrier to …

When near-infrared fluorescence meets supramolecular coordination complexes: Challenges and opportunities of metallacycles/metallacages in precision …

Y Xu, Y Dou, Q Li, H Ye, Y Li, S Qiu, X Xiong, J Li… - Coordination Chemistry …, 2023 - Elsevier
In the past decade, the metallacycles/metallacages have attracted unremitting interest in
biomedical fields, yet visual tracking of their in vivo delivery, targeting ability, biodistribution …

Long wavelength–emissive Ru (II) metallacycle–based photosensitizer assisting in vivo bacterial diagnosis and antibacterial treatment

Y Xu, C Li, X Ma, W Tuo, L Tu, X Li… - Proceedings of the …, 2022 - National Acad Sciences
Ruthenium (Ru) complexes are developed as latent emissive photosensitizers for cancer
and pathogen photodiagnosis and therapy. Nevertheless, most existing Ru complexes are …

Engineered metallacycle‐based supramolecular Photosensitizers for effective Photodynamic Therapy

L Tu, C Li, X Xiong, J Hyeon Kim, Q Li, L Mei… - Angewandte …, 2023 - Wiley Online Library
Although metallacycle‐based supramolecular photosensitizers (PSs) have attracted
increasing attention in biomedicine, their clinical translation is still hindered by their inherent …

Second near-infrared window fluorescence nanoprobes for deep-tissue in vivo multiplexed bioimaging

Y Yang, Y Xie, F Zhang - Advanced drug delivery reviews, 2023 - Elsevier
In vivo multiplexed bioimaging in the second near-infrared window (NIR-II, 1000–1700 nm),
owing to its superiorities of simultaneous multi-channel (multicolor) observations for multiple …

Construction of Long‐Wavelength Emissive Organic Nanosonosensitizer Targeting Mitochondria for Precise and Efficient In Vivo Sonotherapy

X Zhang, C Li, Y Zhang, X Guan, L Mei… - Advanced Functional …, 2022 - Wiley Online Library
As a modern biomedical therapeutic modality, sonodynamic therapy (SDT) presents unique
advantages, including superior tissue penetration capability, temporal–spatial controllability …

NIR-II bioimaging of small molecule fluorophores: From basic research to clinical applications

C Li, X Guan, X Zhang, D Zhou, S Son, Y Xu… - Biosensors and …, 2022 - Elsevier
Due to the low autofluorescence and deep-photo penetration, the second near-infrared
region fluorescence imaging technology (NIR-II, 1000–2000 nm) has been widely utilized in …

Recent progress in metal-organic cages for biomedical application: Highlighted research during 2018–2023

YP Wang, Y Zhang, XH Duan, JJ Mao, M Pan… - Coordination Chemistry …, 2024 - Elsevier
Metal-organic cages (MOCs) are a class of widely used nanosize supramolecular
architectures with specific geometric shapes and confined cavities, constructed from the …

Dimeric pillar [5] arene as a novel fluorescent host for controllable fabrication of supramolecular assemblies and their photocatalytic applications

K Wang, R Zhang, Z Song, K Zhang, X Tian… - Advanced …, 2023 - Wiley Online Library
A dimeric fluorescent macrocycle m‐TPE Di‐EtP5 (meso‐tetraphenylethylene dimeric
ethoxypillar [5] arene) is synthesized based on the meso‐functionalized ethoxy pillar [5] …

Tumor‐targeted nano‐adjuvants to synergize photomediated immunotherapy enhanced antitumor immunity

H Zhu, C Yang, A Yan, W Qiang, R Ruan, K Ma… - View, 2023 - Wiley Online Library
Photomediated immunotherapy explored to combine the anti‐cancer effect of phototherapy
with the immune enhancement ability of immunotherapy, and shown great prospects for …