Strategies to address key challenges of metallacycle/metallacage-based supramolecular coordination complexes in biomedical applications

D Xu, Y Li, S Yin, F Huang - Chemical Society Reviews, 2024 - pubs.rsc.org
Owing to their capacity for dynamically linking two or more functional molecules,
supramolecular coordination complexes (SCCs), exemplified by two-dimensional (2D) …

NIR‐II Fluorescence Imaging‐Guided Oxygen Self‐Sufficient Nano‐Platform for Precise Enhanced Photodynamic Therapy

W Li, H Xin, Y Zhang, C Feng, Q Li, D Kong, Z Sun… - Small, 2022 - Wiley Online Library
Tumor hypoxia and systemic toxicity seriously affect the efficacy of photodynamic therapy
(PDT) and are considered as the “Achilles' heel” of PDT. Herein, to combat such limitations …

Recent advances on the construction of long-wavelength emissive supramolecular coordination complexes for photo-diagnosis and therapy

Z Zhang, H Ye, F Cai, Y Sun - Dalton Transactions, 2023 - pubs.rsc.org
Recently, metal-based drugs have attracted relentless interest in the biomedical field.
However, their short excitation/emission wavelengths and unsatisfactory therapeutic …

Near‐Infrared Bodipy‐Based Molecular Rotors for β‐Amyloid Imaging In Vivo

L Ma, Y Geng, G Zhang, Z Hu, TD James… - Advanced …, 2023 - Wiley Online Library
Abstract β‐amyloid (Aβ) is one of the important biomarkers for diagnosing Alzheimer's
disease (AD). Many near‐infrared probes based on the donor‐π‐acceptor structure have …

Tumor-targeted self-assembled micelles reducing PD-L1 expression combined with ICIs to enhance chemo-immunotherapy of TNBC

H Zhu, K Ma, R Ruan, C Yang, A Yan, J Li, Q Yu… - Chinese Chemical …, 2024 - Elsevier
Immune checkpoint inhibitors (ICIs) therapy targeting programmed cell death ligand 1 (PD-
L1) and programmed death protein 1 (PD-1) had exhibited significant clinical benefits for …

Bent-to-planar Si-rhodamines: a distinct rehybridization lights up NIR-II fluorescence for tracking nitric oxide in the Alzheimer's disease brain

Q Xu, Y Zhang, M Zhu, C Yan, W Mao, WH Zhu… - Chemical …, 2023 - pubs.rsc.org
An ongoing revolution in fluorescence-based technologies has transformed the way we
visualize and manipulate biological events. An enduring goal in this field is to explore high …

Crucial Breakthrough of BODIPY‐Based NIR‐II Fluorescent Emitters for Advanced Biomedical Theranostics

X Hu, Z Fang, C Zhu, Y Yang, Z Yang… - Advanced Functional …, 2024 - Wiley Online Library
Fluorescence imaging in the second near‐infrared window (NIR‐II, 1000–1700 nm) has
aroused immense attention for biomedical applications, offering exceptional advantages …

Phototherapy and Mechanism Exploration of Biofilm and Multidrug‐Resistant Helicobacter pylori by Bacteria‐Targeted NIR Photosensitizer

Y Qiao, Y Ma, Y Tong, W Liu, S Wang, Y Zheng, C Men… - Small, 2023 - Wiley Online Library
Helicobacter pylori (H. pylori) infection has been the leading cause of gastric cancer
development. In recent years, the resistance of H. pylori against antibiotic treatment has …

Engineering rational SERS nanotags for parallel detection of multiple cancer circulating biomarkers

Z Zhang, R Guan, J Li, Y Sun - Chemosensors, 2023 - mdpi.com
Precision cancer medicine necessitates a personalized treatment plan for each individual
patient. Given cancer's heterogeneity and dynamic nature, the plot of patient-specific …

Drug Repurposing‐Based Brain‐Targeting Self‐Assembly Nanoplatform Using Enhanced Ferroptosis against Glioblastoma

J Liang, L Li, H Tian, Z Wang, G Liu, X Duan, M Guo… - Small, 2023 - Wiley Online Library
Glioblastoma (GBM), the most aggressive and lethal form of malignant brain tumor, is a
therapeutic challenge due to the drug filtration capabilities of the blood‐brain barrier (BBB) …