Molecular functions of microRNAs in colorectal cancer: recent roles in proliferation, angiogenesis, apoptosis, and chemoresistance

DES Ellakwa, N Mushtaq, S Khan, A Jabbar… - Naunyn-Schmiedeberg's …, 2024 - Springer
MiRNAs (microRNAs) constitute a group of diminutive molecules of non-coding RNA
intricately involved in regulating gene expression. This regulation is primarily accomplished …

[HTML][HTML] The association of FSCN1 (rs852479, rs1640233) and HOTAIR (rs920778) polymorphisms with the risk of breast cancer in Egyptian women

ER Galal, DA Abdelhakam, LK Ahmed… - Molecular Biology …, 2024 - Springer
Background Breast cancer (BC) is one of the most prevalent cancers that contribute to
mortality among women worldwide. Despite contradictory findings, considerable evidence …

Epigenetic alterations in preeclampsia: a focus on microRNA149 and tetrahydrofolate reductase gene polymorphisms in Egyptian women

DES Ellakwa, LA Rashed, AAA El-Mandoury… - Irish Journal of Medical …, 2024 - Springer
Background Preeclampsia (PE) poses a substantial risk to prenatal and maternal health.
Folic acid (FA) and methylenetetrahydrofolate reductase (MTHFR) play roles in DNA …

The potential impact of microRNA-related functional polymorphisms in the pathogenesis of coronary heart disease

TU Haq, Y Ali, SU Rahman, S Ali, Y Chen, F Jalil… - medRxiv, 2023 - medrxiv.org
MicroRNAs (miRNA) are important post-transcriptional gene regulators. Various populations
have experienced a marked rise in the risk of coronary heart disease (CHD) due to multiple …