International Union of Basic and Clinical Pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function

NM Barnes, GP Ahern, C Becamel, J Bockaert… - Pharmacological …, 2021 - ASPET
5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …

Autoregulation of serotonin neurons: role in antidepressant drug action

G Piñeyro, P Blier - Pharmacological reviews, 1999 - ASPET
The existence of an endogenous vasoconstrictor in blood serum (Stevens and Lee, 1984;
Brodie, 1900) and the presence in the gut of a substance that increases intestinal motility …

Poststroke depression and emotional incontinence: correlation with lesion location

JS Kim, S Choi-Kwon - Neurology, 2000 - AAN Enterprises
Objective: To correlate the location of stroke with poststroke depression (PSD) and
emotional incontinence (PSEI). Methods: The authors prospectively studied 148 patients (94 …

Serotonin1B receptors: from protein to physiological function and behavior

Y Sari - Neuroscience & Biobehavioral Reviews, 2004 - Elsevier
The serotonin (5-HT) 1B receptor is expressed in the central nervous system (CNS) of
rodents and its homologous 5-HT1Dβ receptor is expressed in human. These receptors are …

The mouse 5-hydroxytryptamine 1B receptor is localized predominantly on axon terminals

U Boschert, DA Amara, L Segu, R Hen - Neuroscience, 1994 - Elsevier
The 5-hydroxytryptamine 1B receptor is a serotonin receptor subtype which is expressed
predominantly in the basal ganglia. It has been suggested to play a role in movement and …

Autoradiographic characterisation and localisation of 5-HT1D compared to 5-HT1B binding sites in rat brain

AT Bruinvels, JM Palacios, D Hoyer - Naunyn-Schmiedeberg's archives of …, 1993 - Springer
The regional distribution and the pharmacology of the binding sites labelled with the novel 5-
hydroxytryptamine (serotonin) 5-HT 1B/1D selective radioligand serotonin-O-carboxy-methyl …

Alignment of receptor nomenclature with the human genome: classification of 5-HT1B and 5-HT1D receptor subtypes

PR Hartig, D Hoyer, PPA Humphrey… - Trends in pharmacological …, 1996 - cell.com
As the pharmacological community moves towards obtaining a consensus on the criteria
used to systematically ctassify receptors and ion channeW it has become clear that …

5-Hydroxytryptamine receptor subtypes in vertebrates and invertebrates

F Saudou, R Hen - Neurochemistry international, 1994 - Elsevier
In the last few years, molecular biology has led to the cloning and characterization of several
5-HT receptors (serotonin receptors) in vertebrates and in invertebrates. These studies have …

Psychotropic and neurotropic activity

HG Vogel, WH Vogel - Drug discovery and evaluation: Pharmacological …, 1997 - Springer
The effects of drugs on the central and peripheral nervous systems can be easily recognized
in normal animals. This does not necessarily mean that these effects can be used in therapy …

Differential distribution of [3H] sumatriptan binding sites (5-HT1B, 5-HT1D and 5-HT1F receptors) in human brain: focus on brainstem and spinal cord

ME Castro, J Pascual, T Romon, C Del Arco… - …, 1997 - Elsevier
We report on the autoradiographic distribution of 5-HT1B, 5-HT1D and 5-HT1F receptor
subtypes in human brain, focusing on the brainstem and cervical spinal cord. We have used …