[HTML][HTML] Novel biomarkers used for early diagnosis and tyrosine kinase inhibitors as targeted therapies in colorectal cancer
H Jiang, S Zhou, G Li - Frontiers in pharmacology, 2023 - frontiersin.org
Colorectal cancer (CRC) is the third most common and second most lethal type of cancer
worldwide, presenting major health risks as well as economic costs to both people and …
worldwide, presenting major health risks as well as economic costs to both people and …
[HTML][HTML] High-dose short-term osimertinib treatment is effective in patient-derived metastatic colorectal cancer organoids
KK Iyer, D Poel, A Miggelenbrink, W Kerkhof, J Janssen… - BJC Reports, 2024 - nature.com
Background Most tyrosine kinase inhibitors (TKIs) have failed in clinical trials for metastatic
colorectal cancer (mCRC). To leverage the additional lower-affinity targets that most TKIs …
colorectal cancer (mCRC). To leverage the additional lower-affinity targets that most TKIs …
Targeting CAFs to Improve Anti-PD-1 Checkpoint Immunotherapy
DVF Tauriello - Cancer Research, 2023 - AACR
The tumor microenvironment is a complex ecosystem that drives cancer progression and
restrains immunity. Although immune checkpoint inhibitors have shown strong potential in a …
restrains immunity. Although immune checkpoint inhibitors have shown strong potential in a …
[HTML][HTML] Strategies in overcoming the chemoresistance in colorectal cancer
S Vodenkova, T Buchler, V Vymetalkova - Frontiers in Oncology, 2023 - frontiersin.org
In this Special Topic, entitled" Strategies in Overcoming the Chemoresistance in Colorectal
Cancer", in a collection of ten papers the authors focused on the different aspects that play …
Cancer", in a collection of ten papers the authors focused on the different aspects that play …
[PDF][PDF] Resolving network clusters disparity based on dissimilarity measurements with nonmetric analysis of variance
Classic ANOVA (cA) tests the explanatory power of a partitioning on a set of objects. More fit
for clusters proximity analysis, nonparametric ANOVA (npA) extends to a case where instead …
for clusters proximity analysis, nonparametric ANOVA (npA) extends to a case where instead …
C-KIT receptor on mast cells as a possible target for the treatment of colorectal cancer
A Timelli - 2023 - studenttheses.uu.nl
The role of mast cells (MCs) in the development and progression of colorectal cancer has
long been investigated. A high density of these immune cells, which are able to release …
long been investigated. A high density of these immune cells, which are able to release …