Significance of single-nucleotide variants in long intergenic non-protein coding RNAs
H Zou, LX Wu, L Tan, FF Shang… - Frontiers in Cell and …, 2020 - frontiersin.org
Single-nucleotide variants (SNVs) are the most common genetic variants and universally
present in the human genome. Genome-wide association studies (GWASs) have identified a …
present in the human genome. Genome-wide association studies (GWASs) have identified a …
Mendelian randomization analysis identifies CpG sites as putative mediators for genetic influences on cardiovascular disease risk
The extent to which genetic influences on cardiovascular disease risk are mediated by
changes in DNA methylation levels has not been systematically explored. We developed an …
changes in DNA methylation levels has not been systematically explored. We developed an …
Genetic characterization of endometriosis patients: review of the literature and a prospective cohort study on a Mediterranean population
S Angioni, MN D'Alterio, A Coiana, F Anni… - International journal of …, 2020 - mdpi.com
The pathogenesis of endometriosis is unknown, but some evidence supports a genetic
predisposition. The purpose of this study was to evaluate the recent literature on the genetic …
predisposition. The purpose of this study was to evaluate the recent literature on the genetic …
A common allele increases endometrial Wnt4 expression, with antagonistic implications for pregnancy, reproductive cancers, and endometriosis
M Pavličev, CE McDonough-Goldstein… - Nature …, 2024 - nature.com
The common human SNP rs3820282 is associated with multiple phenotypes including
gestational length and likelihood of endometriosis and cancer, presenting a paradigmatic …
gestational length and likelihood of endometriosis and cancer, presenting a paradigmatic …
Tissue specific regulation of transcription in endometrium and association with disease
STUDY QUESTION Are genetic effects on endometrial gene expression tissue specific
and/or associated with reproductive traits and diseases? SUMMARY ANSWER Analyses of …
and/or associated with reproductive traits and diseases? SUMMARY ANSWER Analyses of …
Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome
Gene expression varies markedly across the menstrual cycle and expression levels for
many genes are under genetic control. We analyzed gene expression and mapped …
many genes are under genetic control. We analyzed gene expression and mapped …
Genetics of endometriosis: a comprehensive review
D Deiana, S Gessa, M Anardu, A Daniilidis… - Gynecological …, 2019 - Taylor & Francis
This review aimed to critically evaluate the review, observational, cohort, and case–control
studies performed so far in order to assess the association between endometriosis and …
studies performed so far in order to assess the association between endometriosis and …
Complex genetics of female fertility
Variation in reproductive lifespan and female fertility have implications for health, population
size and ageing. Fertility declines well before general signs of menopause and is also …
size and ageing. Fertility declines well before general signs of menopause and is also …
Should genetics now be considered the pre-eminent etiologic factor in endometriosis?
GW Montgomery, S Mortlock, LC Giudice - Journal of minimally invasive …, 2020 - Elsevier
Endometriosis is a common, estrogen-dependent, inflammatory disorder characterized by
the growth of endometrial-like tissue at extrauterine locations. Its pathogenesis and …
the growth of endometrial-like tissue at extrauterine locations. Its pathogenesis and …
Genomics of endometriosis: From genome wide association studies to exome sequencing
I Lalami, C Abo, B Borghese, C Chapron… - International journal of …, 2021 - mdpi.com
This review aims at better understanding the genetics of endometriosis. Endometriosis is a
frequent feminine disease, affecting up to 10% of women, and characterized by pain and …
frequent feminine disease, affecting up to 10% of women, and characterized by pain and …