Genetics of endometriosis: State of the art on genetic risk factors for endometriosis
JN Fung, GW Montgomery - Best practice & research Clinical obstetrics & …, 2018 - Elsevier
Developments in high-throughput genotyping technology have driven discovery of genomic
regions associated with an increased risk of endometriosis. In all, 16 genomic regions have …
regions associated with an increased risk of endometriosis. In all, 16 genomic regions have …
LncRNA ZBTB40-IT1 modulated by osteoporosis GWAS risk SNPs suppresses osteogenesis
B Mei, Y Wang, W Ye, H Huang, Q Zhou, Y Chen, Y Niu… - Human Genetics, 2019 - Springer
Previous genome-wide linkage and association studies have identified an osteoporosis-
associated locus at 1p36 that harbors SNPs rs34920465 and rs6426749. The 1p36 locus …
associated locus at 1p36 that harbors SNPs rs34920465 and rs6426749. The 1p36 locus …
Genetic analyses of gynecological disease identify genetic relationships between uterine fibroids and endometrial cancer, and a novel endometrial cancer genetic risk …
Endometriosis, polycystic ovary syndrome (PCOS) and uterine fibroids have been proposed
as endometrial cancer risk factors; however, disentangling their relationships with …
as endometrial cancer risk factors; however, disentangling their relationships with …
GWAS meta-analyses clarify the genetics of cervical phenotypes and inform risk stratification for cervical cancer
Genome-wide association studies (GWAS) have successfully identified associations for
cervical cancer, but the underlying mechanisms of cervical biology and pathology remain …
cervical cancer, but the underlying mechanisms of cervical biology and pathology remain …
Genetic and epigenetic changes in the eutopic endometrium of women with endometriosis: association with decreased endometrial αvβ3 integrin expression
NR Joshi, HR Kohan-Ghadr… - Molecular Human …, 2021 - academic.oup.com
About 40% of women with infertility and 70% of women with pelvic pain suffer from
endometriosis. The pregnancy rate in women undergoing IVF with low endometrial integrin …
endometriosis. The pregnancy rate in women undergoing IVF with low endometrial integrin …
The role of long non-coding RNAs in endometriosis
QJ Hudson, K Proestling, A Perricos, L Kuessel… - International Journal of …, 2021 - mdpi.com
Endometriosis is a chronic gynecological disorder affecting the quality of life and fertility of
many women around the world. Heterogeneous and non-specific symptoms may lead to a …
many women around the world. Heterogeneous and non-specific symptoms may lead to a …
Long noncoding RNAs in endometriosis: Biological functions, expressions, and mechanisms
X Wang, J Zhang, X Liu, B Wei… - Journal of cellular …, 2021 - Wiley Online Library
Endometriosis refers to a benign chronic gynecological disorder, and is defined as the
ectopic growth of endometrium in pelvic cavity. Endometriosis affects about 10% of …
ectopic growth of endometrium in pelvic cavity. Endometriosis affects about 10% of …
[HTML][HTML] Identification of MKNK1 and TOP3A as ovarian endometriosis risk-associated genes using integrative genomic analyses and functional experiments
Y Huang, J Luo, Y Zhang, T Zhang, X Fei… - Computational and …, 2023 - Elsevier
The risk of endometriosis (EM), which is a common complex gynaecological disease, is
related to genetic predisposition. However, it is unclear how genetic variants confer the risk …
related to genetic predisposition. However, it is unclear how genetic variants confer the risk …
Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank
T Olafsdottir, G Thorleifsson, P Sulem… - Communications …, 2020 - nature.com
Pelvic organ prolapse (POP) is a downward descent of one or more of the pelvic organs,
resulting in a protrusion of the vaginal wall and/or uterus. We performed a genome-wide …
resulting in a protrusion of the vaginal wall and/or uterus. We performed a genome-wide …
Global endometrial DNA methylation analysis reveals insights into mQTL regulation and associated endometriosis disease risk and endometrial function
Endometriosis is a leading cause of pain and infertility affecting millions of women globally.
Herein, we characterize variation in DNA methylation (DNAm) and its association with …
Herein, we characterize variation in DNA methylation (DNAm) and its association with …