[HTML][HTML] Effect of CFTR modulator therapy with elexacaftor/tezacaftor/ivacaftor on pulmonary ventilation derived by 3D phase-resolved functional lung MRI in cystic …

F Klimeš, A Voskrebenzev, M Gutberlet, M Speth… - European …, 2024 - Springer
Objectives To investigate whether 3D phase-resolved functional lung (PREFUL)-MRI
parameters are suitable to measure response to elexacaftor/tezacaftor/ivacaftor (ETI) …

[HTML][HTML] Quantification of pulmonary perfusion abnormalities using DCE-MRI in COPD: comparison with quantitative CT and pulmonary function

M Schiwek, SMF Triphan, J Biederer, O Weinheimer… - European …, 2022 - Springer
Objectives Pulmonary perfusion abnormalities are prevalent in patients with chronic
obstructive pulmonary disease (COPD), are potentially reversible, and may be associated …

[HTML][HTML] Outracing lung signal decay–potential of ultrashort echo time MRI

MO Wielpütz, SMF Triphan, Y Ohno… - RöFo-Fortschritte auf …, 2019 - thieme-connect.com
Background Magnetic resonance imaging (MRI) of the pulmonary parenchyma is generally
hampered by multiple challenges related to patient respiratory-and circulation-related …

Automatic airway analysis on multidetector computed tomography in cystic fibrosis: correlation with pulmonary function testing

MO Wielpütz, M Eichinger, O Weinheimer… - Journal of thoracic …, 2013 - journals.lww.com
Purpose: To evaluate the fully automatic quantification of airway dimensions on chest
multidetector computed tomography (MDCT) performed in cystic fibrosis (CF) patients …

[HTML][HTML] Ventilation and perfusion assessed by functional MRI in children with CF: reproducibility in comparison to lung function

S Nyilas, G Bauman, O Pusterla, K Ramsey… - Journal of Cystic …, 2019 - Elsevier
Background Chronic lung diseases such as cystic fibrosis (CF) can be monitored by imaging
and lung function modalities. Magnetic resonance imaging (MRI) techniques such as matrix …

MR imaging of the airways

J Biederer - The British Journal of Radiology, 2023 - academic.oup.com
The need for airway imaging is defined by the limited sensitivity of common clinical tests like
spirometry, lung diffusion (DLCO) and blood gas analysis to early changes of peripheral …

Structural and functional lung impairment in primary ciliary dyskinesia. Assessment with magnetic resonance imaging and multiple breath washout in comparison to …

S Nyilas, G Bauman, O Pusterla, G Sommer… - Annals of the …, 2018 - atsjournals.org
Rationale: Primary ciliary dyskinesia (PCD) is an inherited disorder characterized by
heterogeneous airway disease. Traditional lung function techniques (eg, spirometry) may …

Artificial intelligence in computed tomography for quantifying lung changes in the era of CFTR modulators

G Dournes, CS Hall, MM Willmering… - European …, 2022 - Eur Respiratory Soc
Background Chest computed tomography (CT) remains the imaging standard for
demonstrating cystic fibrosis (CF) airway structural disease in vivo. However, visual scoring …

Longitudinal lung function and structural changes in children with primary ciliary dyskinesia

ML Magnin, P Cros, N Beydon, M Mahloul… - Pediatric …, 2012 - Wiley Online Library
Abstract Background and Objectives Functional and structural lung evaluations are part of
the follow‐up of patients with primary ciliary dyskinesia (PCD). We aimed to evaluate …

Magnetic resonance imaging-based scoring of the diseased lung in the preterm infant with bronchopulmonary dysplasia: UNiforme Scoring of the disEAsed Lung in …

K Förster, H Marchi, S Stöcklein… - … of Physiology-Lung …, 2023 - journals.physiology.org
Neonatal chronic lung disease lacks standardized assessment of lung structural changes.
We addressed this clinical need by the development of a novel scoring system [UNSEAL …