Magnetic resonance imaging of lung perfusion

SMF Triphan, G Bauman, P Konietzke… - Journal of Magnetic …, 2024 - Wiley Online Library
“Lung perfusion” in the context of imaging conventionally refers to the delivery of blood to the
pulmonary capillary bed through the pulmonary arteries originating from the right ventricle …

Early detection and sensitive monitoring of CF lung disease: prospects of improved and safer imaging

MA Mall, M Stahl, SY Graeber… - Pediatric …, 2016 - Wiley Online Library
Recent imaging studies using chest computed tomography (CT) in presymptomatic infants
and young children with cystic fibrosis (CF) diagnosed by newborn screening presented …

Magnetic resonance imaging detects chronic rhinosinusitis in infants and preschool children with cystic fibrosis

O Sommerburg, MO Wielpütz, JP Trame… - Annals of the …, 2020 - atsjournals.org
Rationale: Chronic rhinosinusitis (CRS) contributes to disease burden of patients with cystic
fibrosis (CF). However, its onset and progression in infants and preschool children with CF …

Functional lung MRI in chronic obstructive pulmonary disease: comparison of T1 mapping, oxygen-enhanced T1 mapping and dynamic contrast enhanced perfusion

BJ Jobst, SMF Triphan, O Sedlaczek, A Anjorin… - PLoS …, 2015 - journals.plos.org
Purpose Monitoring of regional lung function in interventional COPD trials requires
alternative endpoints beyond global parameters such as FEV1. T1 relaxation times of the …

[HTML][HTML] HRCT and MRI of the lung in children with cystic fibrosis: comparison of different scoring systems

C Sileo, H Corvol, PY Boelle, E Blondiaux… - Journal of Cystic …, 2014 - Elsevier
Background Chest imaging is essential in the assessment of respiratory disease in cystic
fibrosis (CF). High-resolution computed tomography (HRCT) can detect progressive lung …

Approaches to evaluate lung inflammation in translational research

DK Meyerholz, JC Sieren, AP Beck… - Veterinary …, 2018 - journals.sagepub.com
Inflammation is a common feature in several types of lung disease and is a frequent end
point to validate lung disease models, evaluate genetic or environmental impact on disease …

Longitudinal evaluation of bronchial changes in cystic fibrosis patients undergoing elexacaftor/tezacaftor/ivacaftor therapy using lung MRI with ultrashort echo‐times

M David, I Benlala, S Bui, T Benkert… - Journal of Magnetic …, 2024 - Wiley Online Library
Background Lung magnetic resonance imaging (MRI) with ultrashort echo‐times (UTE‐MRI)
allows high‐resolution and radiation‐free imaging of the lung structure in cystic fibrosis (CF) …

Dynamic perfluorinated gas MRI shows improved lung ventilation in people with cystic fibrosis after elexacaftor/tezacaftor/ivacaftor: an observational study

JL Goralski, SH Chung, AS Ceppe, MZ Powell… - Journal of Clinical …, 2022 - mdpi.com
The availability of highly effective CFTR modulators is revolutionizing the treatment of cystic
fibrosis (CF) and drastically improving outcomes. MRI-based imaging modalities are now …

Echo Time‐Dependence of Observed Lung T1 in Patients With Cystic Fibrosis and Correlation With Clinical Metrics

SMF Triphan, M Stahl, BJ Jobst… - Journal of Magnetic …, 2020 - Wiley Online Library
Background Noninvasive monitoring of early abnormalities and therapeutic intervention in
cystic fibrosis (CF) lung disease using MRI is important. Lung T1 mapping has shown …

PREFUL MRI for Monitoring Perfusion and Ventilation Changes after Elexacaftor-Tezacaftor-Ivacaftor Therapy for Cystic Fibrosis: A Feasibility Study

M Dohna, A Voskrebenzev, F Klimeš… - Radiology …, 2024 - pubs.rsna.org
Purpose To assess the feasibility of monitoring the effects of elexacaftor-tezacaftor-ivacaftor
(ETI) therapy on lung ventilation and perfusion in people with cystic fibrosis (CF), using …