Early cystic fibrosis lung disease: role of airway surface dehydration and lessons from preventive rehydration therapies in mice
Cystic fibrosis (CF) lung disease starts in the first months of life and remains one of the most
common fatal hereditary diseases. Early therapeutic interventions may provide an …
common fatal hereditary diseases. Early therapeutic interventions may provide an …
Volumetric quantification of lung MR signal intensities using ultrashort TE as an automated score in cystic fibrosis
Objectives The study aimed to validate automated quantification of high and low signal
intensity volumes using ultrashort echo-time MRI, with CT and pulmonary function test (PFT) …
intensity volumes using ultrashort echo-time MRI, with CT and pulmonary function test (PFT) …
A semiquantitative MRI-Score can predict loss of lung function in patients with cystic fibrosis: Preliminary results
JF Schaefer, A Hector, K Schmidt, M Teufel… - European …, 2018 - Springer
Objectives To evaluate the applicability of a semiquantitative MRI scoring system (MR-CF-S)
as a prognostic marker for clinical course of cystic fibrosis (CF) lung disease. Methods This …
as a prognostic marker for clinical course of cystic fibrosis (CF) lung disease. Methods This …
Echo Time‐Dependent Observed Lung T1 in Patients With Chronic Obstructive Pulmonary Disease in Correlation With Quantitative Imaging and Clinical Indices
SMF Triphan, O Weinheimer… - Journal of Magnetic …, 2021 - Wiley Online Library
Background There is a clinical need for imaging‐derived biomarkers for the management of
chronic obstructive pulmonary disease (COPD). Observed pulmonary T1 (T1 (TE)) depends …
chronic obstructive pulmonary disease (COPD). Observed pulmonary T1 (T1 (TE)) depends …
Within‐breath changes in respiratory system impedance in children with cystic fibrosis
E Zannin, S Nyilas, KA Ramsey, P Latzin… - Pediatric …, 2019 - Wiley Online Library
Background The aim of this study was to assess within‐breath respiratory system
impedance by the forced oscillation technique (FOT) in children with cystic fibrosis (CF) and …
impedance by the forced oscillation technique (FOT) in children with cystic fibrosis (CF) and …
Rapid 3D in vivo 1H human lung respiratory imaging at 1.5 T using ultra‐fast balanced steady‐state free precession
Purpose To introduce a reproducible, nonenhanced 1H MRI method for rapid in vivo
functional assessment of the whole lung at 1.5 Tesla (T). Methods At different respiratory …
functional assessment of the whole lung at 1.5 Tesla (T). Methods At different respiratory …
[HTML][HTML] Reanalysis of N2-lung clearance index and the comparison to SF6-lung clearance index and magnetic resonance imaging
E Steinke, MO Wielpütz, C Joachim, MA Mall… - Journal of Cystic …, 2024 - Elsevier
Since the finding and correction of an error in previous spiroware software versions
commonly used with the Exhalyzer D for multiple-breath washout (MBW) analysis, there has …
commonly used with the Exhalyzer D for multiple-breath washout (MBW) analysis, there has …
[HTML][HTML] Sensitive structural and functional measurements and 1-year pulmonary outcomes in pediatric cystic fibrosis
MM Willmering, DJ Roach, EL Kramer, LL Walkup… - Journal of Cystic …, 2021 - Elsevier
Background Two functional measurements (multiple breath washout [MBW] and
hyperpolarized 129 Xe ventilation magnetic resonance imaging [129 Xe MRI]) have been …
hyperpolarized 129 Xe ventilation magnetic resonance imaging [129 Xe MRI]) have been …
Multi-layer ventilation inhomogeneity in cystic fibrosis
Differences in regional lung function between the 3rd and 5th intercostal space (ICS) were
explored in 10 cystic fibrosis (CF) patients and compared to 10 lung-healthy controls by …
explored in 10 cystic fibrosis (CF) patients and compared to 10 lung-healthy controls by …
Lung T1 mapping magnetic resonance imaging in the assessment of pulmonary disease in children with cystic fibrosis: a pilot study
Background Assessment tools for early cystic fibrosis (CF) lung disease are limited.
Detecting early pulmonary disease is crucial to increasing life expectancy by starting …
Detecting early pulmonary disease is crucial to increasing life expectancy by starting …