There is no doubt that significant progress has been made in tumor therapy in the past
decades. However, the discovery of new molecules with potential antitumor properties still …

Pancreatic cancer (PC) is a serious gastrointestinal tract disease for which the 5-year
survival rate is less than 10%, even in developed countries such as the USA. The genomic …

Gastrointestinal cancers are a leading cause of cancer morbidity and mortality worldwide
with 4.2 million new cases and 3.2 million deaths estimated in 2020. Despite the advances …

Breast cancer (BC) remains a significant global health challenge for women despite
advancements in early detection and treatment. Isoliquiritigenin (ISL), a compound derived …

Background Alzheimer's disease (AD) is characterized by neuroinflammation linked to
amyloid β (Aβ) aggregation and phosphorylated tau (τ) protein in neurofibrillary tangles …

Pancreatic cancer (PC) is currently recognized as the seventh most prevalent cause of
cancer-related mortality among individuals of both genders. It is projected that a significant …

Osteoarthritis (OA) is a chronic joint disease that causes pathological changes in articular
cartilage, synovial membrane, or subchondral bone. Conventional treatments for OA include …

Glycyrrhiza has a long history of applications and a wide range of pharmacological effects. It
is known as the “king of all herbs”. Glycyrrhiza is effective in clearing heat, detoxifying …

Abstract Background Renal fibrosis with Renin–angiotensin–aldosterone system (RAAS)
activation and oxidative stress are one of the major complications in hypertension. 2 …

The oncoprotein survivin plays a pivotal role in controlling cell division and preventing
apoptosis by inhibiting caspase activation. Its significant contribution to tumorigenesis and …