Cancer remains one of the major health problems all over the world and conventional
therapeutic approaches have failed to attain an effective cure. Tumor microenvironments …

Nanomaterials have been the focus of intensive development and research in the medical
and industrial sectors over the past several decades. Some studies have found that these …

Most research on the toxicology of nanomaterials has focused on the effects of nanoparticles
that enter the body accidentally. There has been much less research on the toxicology of …

Micro and nanoscale drug carriers must navigate through a plethora of dynamic biological
systems prior to reaching their tissue or disease targets. The biological obstacles to drug …

Fullerenes have attracted considerable attention in different fields of science since their
discovery in 1985. Investigations of physical, chemical and biological properties of …

Organ ischemia with inadequate oxygen supply followed by reperfusion (which initiates a
complex of inflammatory responses and oxidative stress) occurs in different clinical …

Fullerene (C60), a third carbon allotrope, is a classical engineered material with the
potential application in biomedicine. One of the biologically most relevant features of C60 is …

The toxicity grade for a bulk material can be approximately determined by three factors
(chemical composition, dose, and exposure route). However, for a nanomaterial it depends …

Fullerene (C60) has shown great potential in drug delivery. In this study, firstly, amine-
functionalized C60 (C60-NH2) was achieved by introducing ethylenediamine onto the …

Fullerenes are soccer ball-shaped molecules composed of carbon atoms, and, when
derivatized with functional groups, they become soluble and can act as photosensitizers …