ACW-02 an Acridine Triazolidine Derivative Presents Antileishmanial Activity Mediated by DNA Interaction and Immunomodulation
SL Albino, WC da Silva Moura, MML Reis, GLS Sousa… - Pharmaceuticals, 2023 - mdpi.com
The present study proposed the synthesis of a novel acridine derivative not yet described in
the literature, chemical characterization by NMR, MS, and IR, followed by investigations of its …
the literature, chemical characterization by NMR, MS, and IR, followed by investigations of its …
An integrated approach for identifying the efficacy and potential mechanisms of TCM against atherosclerosis—Wu-Zhu-Yu decoction as a case study
C Li, C Chi, W Li, Z Li, X Wang, M Wang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Atherosclerosis (AS) is a chronic disease that is
associated with high morbidity. However, therapeutic approaches are limited. Wu-Zhu-Yu …
associated with high morbidity. However, therapeutic approaches are limited. Wu-Zhu-Yu …
Advances in Computational Methods to Discover New NS2B-NS3 Inhibitors Useful Against Dengue and Zika Viruses
IJ dos Santos Nascimento… - Current Topics in …, 2022 - ingentaconnect.com
The Flaviviridae virus family consists of the genera Hepacivirus, Pestivirus, and Flavivirus,
with approximately 70 viral types that use arthropods as vectors. Among these diseases …
with approximately 70 viral types that use arthropods as vectors. Among these diseases …
Advances in Computational Methods to Discover New NS2B-NS3 Inhibitors Useful Against Dengue and Zika viruses.
JDS Nascimento, M Figueiredo da Silva… - Current Topics in …, 2022 - europepmc.org
The Flaviviridae virus family consists of the genera Hepacivirus, Pestivirus, and Flavivirus,
with approximately 70 viral types that use arthropods as vectors. Among these diseases …
with approximately 70 viral types that use arthropods as vectors. Among these diseases …
Computational analysis followed by in vitro studies to explore cytokines (TNF‐α, IL‐6 and IL‐1β) inhibition potential of the new natural molecule polonilignan
Targeting pro‐inflammatory cytokines and their production is found to be of therapeutic
benefit for the regulation of inflammation in various chronic autoimmune diseases. Our …
benefit for the regulation of inflammation in various chronic autoimmune diseases. Our …
Insights on Microsomal Prostaglandin E2 Synthase 1 (mPGES-1) Inhibitors using Molecular Dynamics and MM/PBSA Calculations
IJ dos Santos Nascimento… - Letters in Drug …, 2024 - ingentaconnect.com
Background: Despite being a normal body response against invading agents, inflammation,
when exaggerated, needs to be controlled to minimize damage to the body. There are …
when exaggerated, needs to be controlled to minimize damage to the body. There are …
[PDF][PDF] MOL2NET'23, Conference on Molecular, Biomedical, Computational, & Network Science and Engineering
FFGR Camposa, KJ da Silva Menezesa, W Phyama - sciforum.net
Flavonoids are known to showcase anti-inflammatory abilities. Hence, it is not a wild guess
that they might inhibit NOD-, LRR-and pyrin domain-containing protein 3 (NLRP3) …
that they might inhibit NOD-, LRR-and pyrin domain-containing protein 3 (NLRP3) …