[HTML][HTML] The role of the immune microenvironment in bone, cartilage, and soft tissue regeneration: from mechanism to therapeutic opportunity

Y Xiong, BB Mi, Z Lin, YQ Hu, L Yu, KK Zha… - Military Medical …, 2022 - Springer
Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

The signaling pathways of traditional Chinese medicine in promoting diabetic wound healing

X Zhou, Y Guo, K Yang, P Liu, J Wang - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance The diabetic wound is one of the common chronic
complications of diabetes, which seriously affects patients' quality of life and even causes …

[HTML][HTML] ADSC-exo@ MMP-PEG smart hydrogel promotes diabetic wound healing by optimizing cellular functions and relieving oxidative stress

T Jiang, S Liu, Z Wu, Q Li, S Ren, J Chen, X Xu… - Materials Today Bio, 2022 - Elsevier
Diabetic wound complications are financially costly and difficult to heal in worldwide.
Whereas the therapies of diabetic wound, such as wound dressing, endocrine therapy or …

Impairment of insulin signaling pathway PI3K/Akt/mTOR and insulin resistance induced AGEs on diabetes mellitus and neurodegenerative diseases: a perspective …

K Ramasubbu, V Devi Rajeswari - Molecular and Cellular Biochemistry, 2023 - Springer
Insulin resistance is common in type 2 diabetes mellitus (T2DM), neurodegenerative
diseases, cardiovascular diseases, kidney diseases, and polycystic ovary syndrome …

[HTML][HTML] Exosomes derived from epidermal stem cells improve diabetic wound healing

P Wang, G Theocharidis, IS Vlachos, K Kounas… - Journal of Investigative …, 2022 - Elsevier
Diabetic foot ulceration is a major diabetic complication with unmet needs. We investigated
the efficacy of epidermal stem cells and epidermal stem cells–derived exosomes (ESCs …

Mechanisms of diabetic foot ulceration: a review

H Deng, B Li, Q Shen, C Zhang, L Kuang… - Journal of …, 2023 - Wiley Online Library
Diabetic foot ulcers (DFUs) are associated with complex pathogenic factors and are
considered a serious complication of diabetes. The potential mechanisms underlying DFUs …

Small-molecule kinase inhibitors for the treatment of nononcologic diseases

Z Xie, X Yang, Y Duan, J Han… - Journal of medicinal …, 2021 - ACS Publications
Great successes have been achieved in developing small-molecule kinase inhibitors as
anticancer therapeutic agents. However, kinase deregulation plays essential roles not only …

Naringin-loaded Arabic gum/pectin hydrogel as a potential wound healing material

MA Alsakhawy, DA Abdelmonsif, M Haroun… - International Journal of …, 2022 - Elsevier
Wound healing is a complicated cellular process with overlapping phases. Naringin (NAR);
a flavanone glycoside, possesses numerous pharmacological effects such as anti …

Macrophage polarization in diabetic wound healing

X Wu, W He, X Mu, Y Liu, J Deng, Y Liu, X Nie - Burns & Trauma, 2022 - academic.oup.com
Impaired wound healing is one of the severe complications of diabetes. Macrophages have
been shown to play a vital role in wound healing. In different wound environments …

Photobiomodulation in diabetic wound healing: a review of red and near‐infrared wavelength applications

O Oyebode, NN Houreld… - Cell Biochemistry and …, 2021 - Wiley Online Library
The development of a painless, non‐invasive, and faster way to diabetic wound healing is at
the forefront of research. The complexity associated with diabetic wounds makes it a cause …