In-silico engineering of RNA nanoplatforms to promote the diabetic wound healing
One of the most notable required features of wound healing is the enhancement of
angiogenesis, which aids in the acceleration of regeneration. Poor angiogenesis during …
angiogenesis, which aids in the acceleration of regeneration. Poor angiogenesis during …
Molecular link between circadian clocks and cardiac function: a network of core clock, slave clock, and effectors
Highlights•A network of core clock-slave clock-effectors link the molecular clock to cardiac
function.•The core clock machinery BMAL1: CLOCK regulates circadian rhythm through both …
function.•The core clock machinery BMAL1: CLOCK regulates circadian rhythm through both …
Vascular endothelial growth factor accelerates healing of foot ulcers in diabetic rats via promoting M2 macrophage polarization
F Liu, X Xu, T Sun - Diabetic Medicine, 2024 - Wiley Online Library
Aim The objective was to investigate the specific role and the regulatory mechanism of
vascular endothelial growth factor (VEGF) during wound healing in diabetic foot ulcer (DFU) …
vascular endothelial growth factor (VEGF) during wound healing in diabetic foot ulcer (DFU) …
dECM restores macrophage immune homeostasis and alleviates iron overload to promote DTPI healing
J Zhang, R Si, Y Gao, H Shan, Q Su… - Regenerative …, 2024 - academic.oup.com
Due to its highly insidious and rapid progression, deep tissue pressure injury (DTPI) is a
clinical challenge. Our previous study found that DTPI may be a skeletal muscle injury …
clinical challenge. Our previous study found that DTPI may be a skeletal muscle injury …
Putative epithelial–mesenchymal transitions during salamander limb regeneration: Current perspectives and future investigations
RT Kim, JL Whited - Annals of the New York Academy of …, 2024 - Wiley Online Library
Previous studies have implicated epithelial–mesenchymal transition (EMT) in salamander
limb regeneration. In this review, we describe putative roles for EMT during each stage of …
limb regeneration. In this review, we describe putative roles for EMT during each stage of …
In‐Silico Selection of Wound‐Healing Plant Secondary Molecules and Their Pro‐Healing Activities on Experimental Models
O Casadiego, O Macias, L García… - Chemistry & …, 2023 - Wiley Online Library
This study explored the potential of plant‐derived molecules (PDMs) as a medicinal
treatment for skin wounds. To assess their healing properties, 34 potential drug molecules …
treatment for skin wounds. To assess their healing properties, 34 potential drug molecules …
竞争性内源性RNA 在创面愈合中作用的研究进展
廖银友, 张丕红 - 中华烧伤与创面修复杂志, 2022 - zhsszz.xml-journal.net
创面愈合作为重要的公共卫生问题之一, 一直是世界性难题. 由于独特的生物创面环境,
创面愈合是一个非常复杂的过程, 目前治疗周期长, 疗效欠佳, 患者经济负担重 …
创面愈合是一个非常复杂的过程, 目前治疗周期长, 疗效欠佳, 患者经济负担重 …
Transcriptomic analysis of a diabetic skin-humanized mouse model dissects molecular pathways underlying the delayed wound healing response
C León, F García-García, S Llames, E García-Pérez… - Genes, 2020 - mdpi.com
Defective healing leading to cutaneous ulcer formation is one of the most feared
complications of diabetes due to its consequences on patients' quality of life and on the …
complications of diabetes due to its consequences on patients' quality of life and on the …
[HTML][HTML] Regulating Lars2 in mitochondria: A potential Alzheimer's therapy by inhibiting tau phosphorylation
W Qian, L Yuan, W Zhuge, L Gu, Y Chen, Q Zhuge… - …, 2024 - Elsevier
Driven by the scarcity of effective treatment options in clinical settings, the present study
aimed to identify a new potential target for Alzheimer's disease (AD) treatment. We focused …
aimed to identify a new potential target for Alzheimer's disease (AD) treatment. We focused …
Microenvironmental dynamics of diabetic wounds and insights for hydrogel-based therapeutics
Y Zhao, Y Zhao, B Xu, H Liu… - Journal of Tissue …, 2024 - journals.sagepub.com
The rising prevalence of diabetes has underscored concerns surrounding diabetic wounds
and their potential to induce disability. The intricate healing mechanisms of diabetic wounds …
and their potential to induce disability. The intricate healing mechanisms of diabetic wounds …