A comprehensive review of small molecules targeting PI3K pathway: Exploring the structural development for the treatment of breast cancer

R Dubey, A Sharma, S Gupta, GD Gupta, V Asati - Bioorganic Chemistry, 2023 - Elsevier
Cancer stands as one of the deadliest diseases, ranking second in terms of its global impact.
Despite the presence of numerous compelling theories concerning its origins, none have …

Effects of topical application of CHF6467, a mutated form of human nerve growth factor, on skin wound healing in diabetic mice

A Giuliani, L Lorenzini, VA Baldassarro… - … of Pharmacology and …, 2020 - ASPET
Nerve growth factor (NGF) is the protein responsible for the development and maintenance
of sensory skin innervation. Given the role of appropriate innervation in skin healing, NGF …

[HTML][HTML] The impact of low-level laser therapy (photobiomodulation) on the complications associated with conventional dental treatments and oral disorders: A …

R Bahrami, M Pourhajibagher, F Gharibpour… - Journal of Dental …, 2024 - Elsevier
Oral health-related quality of life (OHRQoL) refers to how oral conditions impact an
individual's social interactions and positive perception of their dental and facial appearance …

Emodin protects against lipopolysaccharide-induced inflammatory injury in HaCaT cells through upregulation of miR-21

Y Song, X Cui, R Zhao, L Hu, Y Li… - … Cells, Nanomedicine, and …, 2019 - Taylor & Francis
Background/aim Pressure ulcers are a disastrous health issue in which inflammation is
involved. Emodin possesses biological properties in inflammation. Our study investigated …

[HTML][HTML] Advanced glycation end products regulate macrophage apoptosis and influence the healing of diabetic foot wound through miR-361-3p/CSF1R and PI3K/AKT …

Y Jin, Y Huang, G Zeng, J Hu, M Li, M Tian, T Lei… - Heliyon, 2024 - cell.com
Abstract Background Diabetic foot ulcers (DFUs) are a severe complication of diabetes.
Persistent inflammation and impaired vascularization present considerable challenges in …

A Plantaginis Semen-Coptidis Rhizoma compound alleviates type 2 diabetic mellitus in mice via modulating AGEs-RAGE pathway

P Liu, X Yan, J Pu, Q Liao, K Wang, J Lan… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Plantaginis Semen-Coptidis Rhizoma Compound
(CQC) was first recorded in Shengji Zonglu. Clinical and experimental studies have reported …

[HTML][HTML] Low-level laser irradiation modulated viability of normal and tumor human lymphocytes in vitro

HS Bagheri, SH Rasta, SM Mohammadi… - Journal of Lasers in …, 2020 - ncbi.nlm.nih.gov
Introduction: Laser radiation is a promising strategy against various malignancies. Recent
studies have shown that the application of low-power laser therapy (LPLT) at different doses …

Facile process of Hibiscus mucilage polymer formulation using Hibiscus rosa-sinensis leaves to treat second-degree burn and excision wounds

I Saha, S Ghosh, S Roy, T Basu… - Biomedical …, 2024 - iopscience.iop.org
Mucilage is a sticky substance found in various plants and microorganisms and is made up
of proteins and polysaccharides. Mucilage from Hibiscus rosa sinensisis is a complex …

[HTML][HTML] The combined effects of a methacrylate powder dressing (Altrazeal Powder) and photobiomodulation therapy on the healing of a severe diabetic foot ulcer in …

R Derakhshan, H Ahmadi, M Bayat… - Journal of Lasers in …, 2022 - ncbi.nlm.nih.gov
Weakened wound healing is a popular, severe complication of patients with diabetes which
poses a risk for foot infection and amputation. Researchers have searched for new …

Growth differentiation factor 10 induces angiogenesis to promote wound healing in rats with diabetic foot ulcers by activating TGF-β1/Smad3 signaling pathway

Q Zhao, J Xu, X Han, Z Zhang, J Qu… - Frontiers in …, 2023 - frontiersin.org
Background Diabetic foot ulcer (DFU) represents a highly-prevalent complication of diabetes
mellitus (DM). Herein, the current study sought to identify the role of growth differentiation …