Tissue engineering has produced innovative tools for cancer research. 3D cancer models
based on molecularly designed biomaterials aim to harness the dimensionality and …

The limitations of traditional two-dimensional (2D) cultures and animal testing, when it
comes to precisely foreseeing the toxicity and clinical effectiveness of potential drug …

Drug-resistant cancer spheroids were fabricated by three-dimensional (3D) bioprinting for
the quantitative evaluation of drug resistance of cancer cells, which is a very important issue …

Cancer-associated fibroblasts (CAFs) are one of the most abundant stromal cells in the
tumor microenvironment which mediate desmoplastic response and are the primary driver …

Simple Summary Development of new therapeutics to treat osteosarcoma is fundamental to
decreasing its current health impact. 3D in vitro models are gaining tremendous momentum …

The fabrication of scaffolds that accurately recreate the architecture of living tissues is a
major challenge in the field of tissue engineering and regenerative medicine. Core–shell …

Osteosarcoma (OS) is the most common primary malignant bone cancer in children and
adolescents. While numerous other cancers now have promising therapeutic advances …

The coordinated migration of invasive tumor cells is a complex and dynamic mechanism
driven by diverse cellular and molecular events. Unfortunately, the inherent heterogeneity …

Lung malignancies accounted for 11% of cancers worldwide in 2020 and remained the
leading cause of cancer deaths. About 80% of lung cancers belong to non-small cell lung …

The pronounced influence of extracellular matrix (ECM) on bone tumor progression and
metastasis have gained increased attention, which is difficult to reflect in current in vitro …