Praziquantel for schistosomiasis: single-drug metabolism revisited, mode of action, and resistance
Schistosomiasis, a major neglected tropical disease, affects more than 250 million people
worldwide. Treatment of schistosomiasis has relied on the anthelmintic drug praziquantel …
worldwide. Treatment of schistosomiasis has relied on the anthelmintic drug praziquantel …
Lack of clinical pharmacokinetic studies to optimize the treatment of neglected tropical diseases: a systematic review
L Verrest, TPC Dorlo - Clinical pharmacokinetics, 2017 - Springer
Abstract Introduction Neglected tropical diseases (NTDs) affect more than one billion
people, mainly living in developing countries. For most of these NTDs, treatment is …
people, mainly living in developing countries. For most of these NTDs, treatment is …
Demonstration of N,N-Dimethyldithiocarbamate as a Copper-Dependent Antibiotic against Multiple Upper Respiratory Tract Pathogens
SV Menghani, A Rivera, M Neubert… - Microbiology …, 2021 - Am Soc Microbiol
Transition metals are necessary cofactors and structural elements in living systems.
Exposure to high concentrations of biologically important transition metals, such as zinc and …
Exposure to high concentrations of biologically important transition metals, such as zinc and …
UHPLC-MS-based metabolomics analysis reveals the process of schistosomiasis in mice
Y Huang, Q Wu, L Zhao, C Xiong, Y Xu… - Frontiers in …, 2020 - frontiersin.org
Metabolomics, as an emerging technology, has been demonstrated to be a very powerful
tool in the study of the host metabolic responses to infections by parasites. Schistosomiasis …
tool in the study of the host metabolic responses to infections by parasites. Schistosomiasis …
Effect of CYP1A2 polymorphism on the pharmacokinetics of agomelatine in Chinese healthy male volunteers
L Song, Q Du, X Jiang, L Wang - Journal of clinical pharmacy …, 2014 - Wiley Online Library
What is known and objective Agomelatine is a melatonin (MT) analogue with agonistic
properties and has been proven to be effective for various types of depressive symptoms …
properties and has been proven to be effective for various types of depressive symptoms …
白藜芦醇及其伍用吡喹酮对小鼠日本血吸虫肝纤维化的治疗作用
陈艳, 肖政 - 中国寄生虫学与寄生虫病杂志, 2013 - cqvip.com
目的探讨白藜芦醇及其伍用吡喹酮防治小鼠血吸虫肝纤维化的作用及机制. 方法80
只昆明小鼠感染日本血吸虫尾蚴(25 条/鼠) 6 周后, 随机均分为4 组. A 组小鼠灌胃吡喹酮500mg …
只昆明小鼠感染日本血吸虫尾蚴(25 条/鼠) 6 周后, 随机均分为4 组. A 组小鼠灌胃吡喹酮500mg …
Disposition of mefloquine and enpiroline is highly influenced by a chronic Schistosoma mansoni infection
K Ingram, U Duthaler, M Vargas, W Ellis… - Antimicrobial agents …, 2013 - Am Soc Microbiol
Chronic Schistosoma mansoni infections lead to severe tissue destruction of the gut wall
and liver and can influence drug disposition. This study aimed to investigate the impact of a …
and liver and can influence drug disposition. This study aimed to investigate the impact of a …
Evidence-based treatment of schistosomiasis in pregnancy
M Barrion, JG Voss - The Nurse Practitioner, 2013 - journals.lww.com
Schistosomiasis is a parasitic infection that causes significant morbidity and mortality,
especially in pregnant women originating from developing countries. Prompt diagnosis and …
especially in pregnant women originating from developing countries. Prompt diagnosis and …
Developing Dithiocarbamate Derivatives as Copper-Dependent Antimicrobials Against S. pneumoniae and Other Pathogens
SV Menghani - 2022 - search.proquest.com
From the ancient Egyptians in 2500 BC using copper pots to prevent contamination of
drinking water to the Greek physician Hippocrates writing about the application of dry copper …
drinking water to the Greek physician Hippocrates writing about the application of dry copper …
New scope on the relationship between rotifers and Biomphalaria alexandrina snails
SF Mossallam, EI Amer, IF Abou—El—Naga - Asian Pacific Journal of …, 2013 - Elsevier
Objective To investigate the effect of rotifer internalization into snail tissue on the
development of schistosomes. Methods Susceptible laboratory–bred Biomphalaria …
development of schistosomes. Methods Susceptible laboratory–bred Biomphalaria …