Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …

The COVID-19 pandemic has surprised the entire population. The world has had to face an
unprecedented pandemic. Only, Spanish flu had similar disastrous consequences. As a …

Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

The yellow‐legged or Asian wasp (Vespa velutina nigrithorax) has spread rapidly across
Europe since its first introduction in France, in 2004. Originally from South‐East Asia, it is …

Hymenoptera venom–triggered anaphylaxis (HVA) affects up to 8.9% of the general
population and is the most frequent cause of anaphylaxis in adults, accounting for …

Objective: To define the sensitization pattern of patients with anaphylaxis to Vespa velutina
nigrithorax (VVN). Methods: One-hundred consecutive Spanish patients with Hymenoptera …

The true rate of anaphylaxis is unknown due to a number of factors, such as misdiagnosis,
miscoding and undernotification. Moreover, there is lack of information about anaphylaxis …

The impact on health‐related quality of life (HRQL) plays a key role for patients suffering
from allergies and anaphylaxis. In this narrative review we review the HRQL in allergic …

Tryptase is a serin-protease produced and released by mast cells after IgE-mediated or non-
IgE mediated stimuli. We here review the various aspects related to the molecular …

Measurement of transiently elevated tryptase levels shortly after a severe reaction can help
elucidate mechanism behind the reaction in identifying mast cell activation. Hymenoptera …