[HTML][HTML] Mechanistic insight into diabetic wounds: Pathogenesis, molecular targets and treatment strategies to pace wound healing

S Patel, S Srivastava, MR Singh, D Singh - Biomedicine & …, 2019 - Elsevier
Wound management in diabetic patient is of an extreme clinical and social concern. The
delayed and impaired healing makes it more critical for research focus. The research on …

Therapeutic strategies for enhancing angiogenesis in wound healing

AP Veith, K Henderson, A Spencer, AD Sligar… - Advanced drug delivery …, 2019 - Elsevier
The enhancement of wound healing has been a goal of medical practitioners for thousands
of years. The development of chronic, non-healing wounds is a persistent medical problem …

Glucose-responsive multifunctional metal–organic drug-loaded hydrogel for diabetic wound healing

J Yang, WN Zeng, P Xu, X Fu, X Yu, L Chen, F Leng… - Acta biomaterialia, 2022 - Elsevier
As the incidence of diabetes increases, its complication, diabetic foot ulcers, has become the
main type of clinically chronic refractory wounds. Due to the hyperglycemic …

Potential applications of nanomaterials and technology for diabetic wound healing

Q Bai, K Han, K Dong, C Zheng, Y Zhang… - International journal …, 2020 - Taylor & Francis
Diabetic wound shows delayed and incomplete healing processes, which in turn exposes
patients to an environment with a high risk of infection. This article has summarized current …

An injectable self-healing coordinative hydrogel with antibacterial and angiogenic properties for diabetic skin wound repair

H Chen, R Cheng, X Zhao, Y Zhang, A Tam, Y Yan… - NPG Asia …, 2019 - nature.com
We report here an injectable, self-healing coordinative hydrogel with antibacterial and
angiogenic properties for diabetic wound regeneration. The hydrogel was prepared by …

An antibacterial and proangiogenic double-layer drug-loaded microneedle patch for accelerating diabetic wound healing

S Gao, W Zhang, X Zhai, X Zhao, J Wang… - Biomaterials …, 2023 - pubs.rsc.org
Diabetic wounds are difficult to heal because of bacterial infections and insufficient
angiogenesis. Herein, we report a double-layer drug-loaded microneedle patch with …

Anti-inflammation biomaterial platforms for chronic wound healing

Z Xu, B Liang, J Tian, J Wu - Biomaterials science, 2021 - pubs.rsc.org
Nowadays, there has been an increase in the number of people with chronic wounds, which
has resulted in serious health problems worldwide. The rate-limiting stage of chronic wound …

[Retracted] Exosomes Derived from Human Bone Marrow Mesenchymal Stem Cells Stimulated by Deferoxamine Accelerate Cutaneous Wound Healing by Promoting …

J Ding, X Wang, B Chen, J Zhang… - BioMed research …, 2019 - Wiley Online Library
The exosomes are derived from mesenchymal stem cells (MSCs) and may be potentially
used as an alternative for cell therapy, for treating diabetic wounds, and aid in angiogenesis …

Bioactive injectable hydrogels containing desferrioxamine and bioglass for diabetic wound healing

L Kong, Z Wu, H Zhao, H Cui, J Shen… - … applied materials & …, 2018 - ACS Publications
Diabetic wound is hard to heal mainly because of the difficulty in vascularization in the
wound area. Accumulating results have shown that desferrioxamine (DFO) can promote …

Diabetic foot ulcers: current advances in antimicrobial therapies and emerging treatments

JM Ramirez-Acuña, SA Cardenas-Cadena… - Antibiotics, 2019 - mdpi.com
Diabetic foot ulcers (DFUs) are very important diabetes-related lesions that can lead to
serious physical consequences like amputations of limbs and equally severe social …