[HTML][HTML] Recent advances in peptide-based therapies for obesity and type 2 diabetes

CJ Bailey, PR Flatt, JM Conlon - Peptides, 2024 - Elsevier
Options for the treatment of type 2 diabetes mellitus (T2DM) and obesity have recently been
expanded by the results of several large clinical trials with incretin-based peptide therapies …

Real-World Use of Oral Semaglutide in Adults with Type 2 Diabetes in the PIONEER REAL Netherlands Multicentre, Prospective, Observational Study

W van Houtum, P Schrömbges, H Amadid… - Diabetes Therapy, 2024 - Springer
Introduction In this phase 4, multicentre, prospective, non-interventional PIONEER REAL
Netherlands study, we assessed clinical outcomes associated with once-daily oral …

Once‐weekly semaglutide use in patients with type 2 diabetes: Results from the SURE France multicentre, prospective, observational study

K Mohammedi, N Belhatem… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aims Real‐world data are required to support glucagon‐like peptide‐1 receptor agonist use
in type 2 diabetes (T2D). SURE France assessed once‐weekly semaglutide in adults with …

Blockbuster Medications for Obesity: A Primer for Nephrologists

EM Zeitler, K Dabb, D Nadeem, CD Still… - American Journal of …, 2023 - Elsevier
The prevalence of obesity in the United States and across the world continues to climb,
imparting increased risk of chronic disease. This impact is doubly felt in nephrology because …

Administration errors of compounded semaglutide reported to a poison control center—Case series

JE Lambson, SC Flegal, AR Johnson - Journal of the American Pharmacists …, 2023 - Elsevier
Background We aimed to increase pharmacists' and regulatory agencies' awareness of
emerging issues regarding current practices of semaglutide use in the community that has …

GLP-1 receptor agonist improves metabolic disease in a pre-clinical model of lipodystrophy

A Roumane, GD Mcilroy, N Sommer, W Han… - Frontiers in …, 2024 - frontiersin.org
Aims Individuals with lipodystrophies typically suffer from metabolic disease linked to
adipose tissue dysfunction including lipoatrophic diabetes. In the most severe forms of …

The cost-effectiveness analysis of semaglutide for the treatment of adult and adolescent patients with overweight and obesity: a systematic review

AS Asiabar, MA Rezaei, D Jafarzadeh, S Rajaei… - European Journal of …, 2024 - Springer
Purpose The present study aimed to systematically collect and synthesize available cost-
effectiveness studies of semaglutide in patients with obesity or overweight in comparison …

The effect of incretin-based drugs on the riks of acute pancreatitis: a review

A Czaplicka, B Kaleta - Journal of Diabetes & Metabolic Disorders, 2024 - Springer
Objectives In recent years, new hypoglycaemic drugs that affect the incretin system have
become increasingly popular in the treatment of type 2 diabetes mellitus (T2DM): glucagon …

[HTML][HTML] Semaglutide in Heart Failure: A Systematic Review of Outcomes of Semaglutide in Heart Failure Patients

N Gupta, TD Uwawah, K Singh, H Madan, S Kumar… - Cureus, 2024 - ncbi.nlm.nih.gov
Heart failure (HF) stands as a formidable challenge in global healthcare casting a long
shadow over both morbidity and mortality. A significant interplay between HF and type 2 …

Enhanced cardiac mitochondrial biogenesis by nitro-oleic acid remedies diastolic dysfunction in a mouse model of heart failure with preserved ejection fraction

M Mueller, T Schubert, C Welke, TJ Schulz… - bioRxiv, 2024 - biorxiv.org
Prevalence of heart failure with preserved ejection fraction (HFpEF) is increasing, while
treatment options are inadequate. Hypertension and obesity-related metabolic dysfunctions …