Coronary atherosclerosis is a chronic pathological process that involves inflammation
together with endothelial dysfunction and lipoprotein dysregulation. Experimental studies …

Rationale: Epidemiological evidence indicates that exposures to fine particulate matter air
pollution (PM2. 5) contribute to global burden of disease, primarily as a result of increased …

Studies analyzing heterochronic parabiosis mice models showed that molecules in the
blood of young mice rejuvenate aged mice. Therefore, blood-based therapies have become …

Atherosclerosis is a chronic inflammatory disease, and the increased expression of
adhesion molecules on vascular smooth muscle cells contributes to the progression of …

Background Numerous epidemiological studies support an inverse association between
serum bilirubin levels and the incidence of cardiovascular disease; however, the mechanism …

Background: Over the last decades, the role of inflammation and immune system activation
in the initiation and progression of coronary artery disease (CAD) has been established …

Prognosis of heart failure remains poor, and it is urgent to find new therapies for this critical
condition. Oxygen and metabolites are delivered through capillaries; therefore, they have …

This work is devoted to the chemical synthesis of sulfated chitosan and its experimental
verification in an animal model of early atherosclerosis. The method of chitosan …

Recently, endothelial-mesenchymal transition (EndMT) has been demonstrated to play an
important role in the development of atherosclerosis, the molecular mechanisms of which …

Retinal pigment epithelial (RPE) degeneration is potentially involved in the pathogenesis of
several retinal degenerative diseases. mTORC1 signaling is shown as a crucial regulator of …