Anti-glycan antibodies: roles in human disease

JS Temme, DL Butler, JC Gildersleeve - Biochemical Journal, 2021 - portlandpress.com
Carbohydrate-binding antibodies play diverse and critical roles in human health.
Endogenous carbohydrate-binding antibodies that recognize bacterial, fungal, and other …

Synthetic carbohydrate based anti-fungal vaccines

VB Krylov, NE Nifantiev - Drug Discovery Today: Technologies, 2020 - Elsevier
Emerging growth of antimycotic resistance among fungal pathogens stimulates the
development of corresponding vaccines and therapeutic monoclonal antibodies for active …

Defining galactomannan positivity in the updated EORTC/MSGERC consensus definitions of invasive fungal diseases

T Mercier, E Castagnola, KA Marr… - Clinical Infectious …, 2021 - academic.oup.com
The consensus definitions of invasive fungal diseases from the EORTC/MSGERC were
recently revised and updated. They now include consensus cutoff values for the …

Mannan detecting C-type lectin receptor probes recognise immune epitopes with diverse chemical, spatial and phylogenetic heterogeneity in fungal cell walls

I Vendele, JA Willment, LM Silva, AS Palma… - PLoS …, 2020 - journals.plos.org
During the course of fungal infection, pathogen recognition by the innate immune system is
critical to initiate efficient protective immune responses. The primary event that triggers …

Biotinylated Oligo-α-(1 → 4)-d-galactosamines and Their N-Acetylated Derivatives: α-Stereoselective Synthesis and Immunology Application

ED Kazakova, DV Yashunsky, VB Krylov… - Journal of the …, 2020 - ACS Publications
Using 3-O-benzoyl-4, 6-O-di-tert-butylsilylidene-2-azido-2-deoxy-selenogalactoside,
biotinylated oligo-α-(1→ 4)-d-galactosamines comprising from two to six GalN units were …

Novel mouse monoclonal antibodies specifically recognizing β-(1→ 3)-D-glucan antigen

AL Matveev, VB Krylov, YA Khlusevich, IK Baykov… - PLoS …, 2019 - journals.plos.org
β-(1→ 3)-D-Glucan is an essential component of the fungal cell wall. Mouse monoclonal
antibodies (mAbs) against synthetic nona-β-(1→ 3)-D-glucoside conjugated with bovine …

Synthetic oligosaccharides mimicking fungal cell wall polysaccharides

VB Krylov, NE Nifantiev - The Fungal Cell Wall: An Armour and a Weapon …, 2020 - Springer
The cell wall of pathogenic fungi is highly important for the development of fungal infections
and is the first cellular component to interact with the host immune system. The fungal cell …

Cell wall of Aspergillus fumigatus: Variability and response to stress

JP Latgé - Fungal Biology, 2023 - Elsevier
The fungal cell is surrounded by a thick cell wall which obviously play an essential role in
the protection of the fungus against external aggressive environments. In spite of 50 years of …

Synthesis of biotin-tagged chitosan oligosaccharides and assessment of their immunomodulatory activity

YE Tsvetkov, E Paulovičová, L Paulovičová… - Frontiers in …, 2020 - frontiersin.org
Chitin, a polymer of β-(1→ 4)-linked N-acetyl-d-glucosamine, is one of the main
polysaccharide components of the fungal cell wall. Its N-deacetylated form, chitosan, is …

[HTML][HTML] Nano-biosensor based on the combined use of the dynamic and static light scattering for Aspergillus galactomannan analysis

MK Alenichev, AD Levin, AA Yushina… - Sensing and Bio …, 2022 - Elsevier
A biosensor based on the analyte-induced aggregation of functionalized nanoparticles
recorded using two optical signals of different physical nature is developed. The …