Memories of positive experiences link places, events, and reward outcomes. These
memories recruit interactions between the hippocampus and nucleus accumbens (NAc) …

Reconsolidation is a putative neuronal process in which the retrieval of a previously
consolidated memory returns it to a labile state that is once again subject to stabilization …

Complete and dorsal hippocampal lesions impaired spatial performance on 2 working
memory tasks: rewarded alternation on the T maze and matching to position in the water …

Aging and increased amyloid burden are major risk factors for cognitive diseases such as
Alzheimer's disease (AD). Effective therapies for these diseases are lacking. Here, we …

Anxiety disorders are a diverse group of clinical states. Post-traumatic stress disorder
(PTSD) and generalized anxiety disorder (GAD), eg, share elevated anxiety symptoms, but …

The hippocampus (HPC) has been traditionally considered to subserve mnemonic
processing and spatial cognition. Over the past decade, however, there has been increasing …

BACKGROUND: As a test of plausibility for the hypothesis that schizophrenia can result from
abnormal brain, especially cerebral cortical, development, these studies examined whether …

CREB is critical for long-lasting synaptic and behavioral plasticity in invertebrates. Its role in
the mammalian hippocampus is less clear. We have interfered with CREB family …

How autobiographical memories are represented in the human brain and whether this
changes with time are questions central to memory neuroscience. Two regions in particular …

The neural mechanisms for the formation of declarative memory (memory for facts and
events) are believed to be integrated from processes mediated by hippocampal long-term …