AIM The “2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial
Fibrillation” provides recommendations to guide clinicians in the treatment of patients with …

Atrial fibrillation (AF) is the most frequent arrhythmia managed in clinical practice, and it is
linked to an increased risk of death, stroke, and peripheral embolism. The Global Burden of …

Previous genome-wide association studies (GWASs) of stroke—the second leading cause of
death worldwide—were conducted predominantly in populations of European ancestry …

Summary Each year, the American Heart Association (AHA), in conjunction with the National
Institutes of Health and other government agencies, brings together in a single document the …

Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …

Atrial fibrillation (AF) affects more than 33 million individuals worldwide and has a complex
heritability. We conducted the largest meta-analysis of genome-wide association studies …

Clinical measurements can be viewed as useful intermediate phenotypes to promote
understanding of complex human diseases. To acquire comprehensive insights into the …

Atrial fibrillation (AF) is a common cardiac arrhythmia resulting in increased risk of stroke.
Despite highly heritable etiology, our understanding of the genetic architecture of AF …

Background: The long-term probability of developing atrial fibrillation (AF) considering
genetic predisposition and clinical risk factor burden is unknown. Methods: We estimated the …

Atrial fibrillation is a common heart rhythm disorder that leads to an increased risk for stroke
and heart failure. Atrial fibrillation is a complex disease with both environmental and genetic …