[HTML][HTML] Global burden of Clostridium difficile infections: a systematic review and meta-analysis

E Balsells, T Shi, C Leese, I Lyell, J Burrows… - Journal of global …, 2019 - ncbi.nlm.nih.gov
Background Clostridium difficile is a leading cause of morbidity and mortality in several
countries. However, there are limited evidence characterizing its role as a global public …

[引用][C] Bayesian evolutionary analysis with BEAST

AJ Drummond, RR Bouckaert - 2015 - Cambridge University Press

[HTML][HTML] The role of vaccines in preventing bacterial antimicrobial resistance

KU Jansen, C Knirsch, AS Anderson - Nature medicine, 2018 - nature.com
Antimicrobial resistance (AMR) and the associated morbidity and mortality due to bacterial
pathogens have been increasing globally to alarming levels. The World Health Organization …

Within-host evolution of bacterial pathogens

X Didelot, AS Walker, TE Peto, DW Crook… - Nature Reviews …, 2016 - nature.com
Whole-genome sequencing has opened the way for investigating the dynamics and
genomic evolution of bacterial pathogens during the colonization and infection of humans …

Clostridium difficile infection: epidemiology, diagnosis and understanding transmission

JSH Martin, TM Monaghan, MH Wilcox - … reviews Gastroenterology & …, 2016 - nature.com
Clostridium difficile infection (CDI) continues to affect patients in hospitals and communities
worldwide. The spectrum of clinical disease ranges from mild diarrhoea to toxic megacolon …

[HTML][HTML] Diverse Sources of C. difficile Infection Identified on Whole-Genome Sequencing

DW Eyre, ML Cule, DJ Wilson, D Griffiths… - … England Journal of …, 2013 - Mass Medical Soc
Background It has been thought that Clostridium difficile infection is transmitted
predominantly within health care settings. However, endemic spread has hampered …

[HTML][HTML] Effects of control interventions on Clostridium difficile infection in England: an observational study

KE Dingle, X Didelot, TP Quan, DW Eyre… - The Lancet Infectious …, 2017 - thelancet.com
Summary Background The control of Clostridium difficile infections is an international clinical
challenge. The incidence of C difficile in England declined by roughly 80% after 2006 …

Update on antimicrobial resistance in Clostridium difficile: resistance mechanisms and antimicrobial susceptibility testing

Z Peng, D Jin, HB Kim, CW Stratton, B Wu… - Journal of clinical …, 2017 - Am Soc Microbiol
Oral antibiotics such as metronidazole, vancomycin and fidaxomicin are therapies of choice
for Clostridium difficile infection. Several important mechanisms for C. difficile antibiotic …

Microbiota transplantation restores normal fecal bile acid composition in recurrent Clostridium difficile infection

AR Weingarden, C Chen, A Bobr… - American Journal …, 2014 - journals.physiology.org
Fecal microbiota transplantation (FMT) has emerged as a highly effective therapy for
refractory, recurrent Clostridium difficile infection (CDI), which develops following antibiotic …

Recent advances in the understanding of antibiotic resistance in Clostridium difficile infection

P Spigaglia - Therapeutic advances in infectious disease, 2016 - journals.sagepub.com
Clostridium difficile epidemiology has changed in recent years, with the emergence of highly
virulent types associated with severe infections, high rates of recurrences and mortality …