Cancer stem cells (CSCs) are a subpopulation of cancer cells with functions similar to those
of normal stem cells. Although few in number, they are capable of self-renewal, unlimited …

Anticancer drug nephrotoxicity is an important and increasing adverse drug event that limits
the efficacy of cancer treatment. The kidney is an important elimination pathway for many …

Exosomes are messengers for intercellular communication and signal transduction. Circular
RNA (circRNA) abnormal expression and regulation are involved in the occurrence and …

Simple Summary Non-Small-Cell Lung Cancer (NSCLC) is the primary cause of cancer-
related death worldwide. Patients carrying Epidermal Growth Factor Receptor (EGFR) …

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) are
standard of care in the first-line (1L) setting for patients with metastatic non–small cell lung …

Epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase and mutations in
EGFR is a major driver force of lung cancer. EGFR tyrosine kinase inhibitors (TKIs) are …

MET amplification (MET amp), a mechanism of acquired resistance to EGFR tyrosine kinase
inhibitors, occurs in up to 30% of patients with non-small-cell lung cancer (NSCLC) …

Lung adenocarcinoma is the most common form of lung cancer, accounting for 60% of non-
small cell lung cancer (NSCLC) cases in Asian patients. Importantly, nearly half of these …

Non‑small cell lung cancer (NSCLC) is a malignant tumor with a high morbidity and mortality
rate that is a threat to human health. With the development of molecular targeted research …

Cancer is one of the leading causes of death worldwide and remains a major public health
challenge. The introduction of more sensitive and powerful technologies has permitted the …